PEP-dependent, phosphoryl transfer-driven group translocators of the
bacterial phosphoenolpyruvate:sugar phosphotransferase system are the
best characterized group translocators included in TC category 4. The
product of the reaction, derived from extracellular sugar, is a
cytoplasmic sugar-phosphate. The enzymatic constituents, catalyzing
sugar phosphorylation, are superimposed on the transport process in a
tightly coupled process. The PTS is also involved in regulation and chemotaxis (Barabote & Saier et al., 2005; Lengeler & Jahreis et al., 2009).