TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameOrganismal TypeExample
4.A.1.1.1
Glucose porter (PtsG) (transports D-glucose and α-methyl-D-glucopyranoside)
Bacteria
Glucose IICB - IIA complex of E. coli
4.A.1.1.2
N-Acetyl glucosamine (NAG) porter (NagE)
Bacteria
NAG IICBA complex of E. coli
4.A.1.1.3
Maltose porter (MalX)
Bacteria
Maltose IICB complex (MalX) of E. coli
4.A.1.1.4
The α-glucoside-specific IICB (MalB) (substrates probably include glucosyl-α-fructose disaccharides: trehalurose (α-1,1), turanose (α-1,3), malturose (α-1,4), leucrose (α-1,5) and palatinose (α-1,6)).
Bacteria
The α-glucoside IICB, MalB of Fusobacterium mortiferum
4.A.1.1.5
N-Acetylglucosamine (NAG) porter (PtsBC1C2)(also may facilitate xylose transport)
Bacteria
The NAG IICC'B complex of Streptomyces olivaceoviridis (IIA not identified)
IICNag (PtsC1)
IIC'Nag (PtsC2)
IIBNag (PtsB)
4.A.1.1.6
The glucosamine IICBA porter (GamP) (40% identical to 4.A.1.1.2)
Bacteria
GamP of Bacillus subtilis (gi2632521)
4.A.1.1.7
The N-acetylglucosamine IICB porter (NagP; YflF) (45% identical to 4.A.1.1.2)
Bacteria
NagP of Bacillus subtilis (gi2443228)
4.A.1.1.8

The maltose IICB porter (MalP; GlvC) (56% identical to 4.A.1.1.4) (Yamamoto et al., 2001).

Bacteria

MalP of Bacillus subtilis (IICBA) (P54715)
4.A.1.1.9
The glucose IICBA porter (PtsG) 44% identical to 4.A.1.1.1)
Bacteria
PtsG of Bacillus subtilis (P20166)
4.A.1.1.10
The α-glucoside-specific IICB, AglB (transports glucose, methyl-α-glucoside, maltitol, isomaltose, trehalulose α(1→1), turanose α(1→3), maltulose α(1→4), leucrose α(1→5), and palatinose α(1→6), but not sucrose (most resembles 4.A.1.1.4 and 4.A.1.1.8) (Pikis et al., 2006)
Bacteria
Glucose/α-glucoside IICB complex of Klebsiella pneumoniae (Q9AGA7)
4.A.1.1.11
The maltose/maltotriose porter, MalT (31% identical to 4.A.1.1.9) (Webb et al., 2007)
Bacteria
MalT IICBA of Streptococcus mutans (Q8DS05)
4.A.1.1.12
Maltose/Maltotriose PTS transporter, MalT (Shelburne et al., 2008) 631aas (68% identical to 4.A.1.1.11 from S. mutans
Bacteria
MalT IICBA of Streptococcus pyogenes (Q48WG5)
4.A.1.2.1
Sucrose porter (ScrA)
Bacteria
Sucrose IIBC complex (ScrA) of plasmid pUR400 from Salmonella typhimurium
4.A.1.2.2
β-Glucoside porter (BglF)
Bacteria
Bgl IIBCA complex of E. coli
4.A.1.2.3
β-Glucoside [arbutin-salicin-cellobiose] (ASC) porter (AscF)
Bacteria
ASC IICB complex of E. coli
4.A.1.2.4
Trehalose porter (TreB)
Bacteria
Trehalose IIBC complex of E. coli
4.A.1.2.5
β-glucoside (methyl-β-glucoside, salicin, arbutin) porter, BglF [a V317A or V317M mutation allows it to transport cellobiose as well] (Kotrba et al., 2003)
Bacteria
β-glucoside IIBCA (BglF) of Corynebacterium glutamicum
4.A.1.2.6
β-glucoside (Aesculin/arbutin) porter, BglP (Cote et al., 2000; Cote and Honeyman, 2003)
Bacteria
β-glucoside IIBCA (BglP) of Streptococcus mutans (AAF89975)
4.A.1.2.7
N-Acetylmuramic acid porter, MurP (YfeV) (Dahl et al., 2004)
Bacteria
N-Acetylmuramate IIBC (MurP or YfeV) of E. coli (P77272)
4.A.1.2.8
Trehalose porter, IIBC (TreP) (38% identical to 4.A.1.2.4)
Bacteria
TreP of Bacillus subtilis (P39794)
4.A.1.2.9
Sucrose porter, IIBC (SacP) (55% identical to 4.A.1.2.1)
Bacteria
SacP of Bacillus subtilis (P05306)
4.A.1.2.10
Sucrose porter and regulatory sensor, IIBC (SacX) (43% identical to 4.A.1.2.1)
Bacteria
SacX of Bacillus subtilis (P15400)
4.A.1.2.11
Aryl β-glucoside porter, IIBCA (BglP; SytA) (35% identical to 4.A.1.2.2)
Bacteria
BglP of Bacillus subtilis (P40739)
4.A.1.2.12
The sucrose porter, PtsS (regulated by SugR which also regulates other enzymes II) (Engels and Wendisch, 2007)
Bacteria
PtsS (IIBCA) complex of Corynebacterium glutamicum (Q8NMD6)