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5.A.1.4.1
Mercury resistance protein; mercuric ion reductase, MerA

Accession Number:P30344
Protein Name:MER4 aka MerA
Length:319
Molecular Weight:31553.00
Species:Streptomyces lividans [1916]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Electrons, Mercury

Cross database links:

Pfam: PF02683   

Gene Ontology

GO:0016020 C:membrane
GO:0046872 F:metal ion binding
GO:0017004 P:cytochrome complex assembly
GO:0055114 P:oxidation reduction
GO:0046689 P:response to mercury ion

References (1)

[1] “Cloning and DNA sequence analysis of the mercury resistance genes of Streptomyces lividans.”  Sedlmeier R.et.al.   1494353

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNGLLALAFA AGMLAPVNPC GFALLPAWIT AALGDSDASP LPVRLTRALR SGAALTLGFA 
61:	GTLAAAGLIV SAGARALIQA APWLGLATGI LLLLLGAVML TGRTPSLRLH LTTSTRRSAG 
121:	PPTARRMAAF GVGYAAASLS CTFGVLLAVI AQAQATASFA GLLAVFAAYA AGSAAVLLLV 
181:	AVTTAAAGAA LTRKITALAR HGTRITAAVL VLTGAYLAWY WYPAATGGAT TAAPGGGLAT 
241:	FSATATAWIQ AHTTAIAVTA VVVVLAVAAA AIRHRTRQPA RHSTPTGTAP SAAAADDCCA 
301:	PLPVPTPAST DRDSDGHCC