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5.a.1.2.1
Cytochrome c-type biogenesis protein, CcdA

Accession Number:P45706
Protein Name:CcdA
Length:235
Molecular Weight:26007.00
Species:Bacillus subtilis [1423]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Electrons

Cross database links:

HEGENOM: HBG733703
RefSeq: NP_389676.1   
Entrez Gene ID: 937140   
Pfam: PF02683   
KEGG: bsu:BSU17930   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0017004 P:cytochrome complex assembly
GO:0055114 P:oxidation reduction
GO:0030435 P:sporulation resulting in formation of a cel...

References (5)

[1] “New genes in the 170 degrees region of the Bacillus subtilis genome encode DNA gyrase subunits, a thioredoxin, a xylanase and an amino acid transporter.”  Rose M.et.al.   8969507
[2] “Identification and characterization of the ccdA gene, required for cytochrome c synthesis in Bacillus subtilis.”  Schioett T.et.al.   9068642
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “Efficient spore synthesis in Bacillus subtilis depends on the CcdA protein.”  Schioett T.et.al.   10781554
[5] “Mutations in the thiol-disulfide oxidoreductases BdbC and BdbD can suppress cytochrome c deficiency of CcdA-defective Bacillus subtilis cells.”  Erlendsson L.S.et.al.   11844773

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGDVNYFLTF GAGFLSFISP CCLPLYPAFL SYITGVSMDD VKTEKLLLQK RSLFHTLCFL 
61:	LGFSVIFIAL GYGTSFIGSL FRDYHDAIRQ IGALLIILFG FITLGVFRPE AMMKERRIHF 
121:	KHKPSGFLGS VLIGMAFAAG WTPCTGPILA AVITLAGTNP GSAVPYMMLY VLGFAVPFLL 
181:	LSFFITKLKW IRKNQLFIMK AGGVLMIVIG VLLFFNWMSL IIILLSDLFG GFTGF