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8.A.103.1.2
SCAMP2 of 329 aas and 4 TMSs.  Required for vesicle fusion pore formation (Liu et al. 2005).  Interacts directly with the serotonin transporter and promotes its localization to the plasma membrane (Müller et al. 2006). It also interacts directly with the dopamine transporter, DAT, to regluate its activity and localization (Fjorback et al. 2011).

Accession Number:O15127
Protein Name:Secretory carrier-associated membrane protein 2
Length:329
Molecular Weight:36649.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Golgi apparatus1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSAFDTNPFA DPVDVNPFQD PSVTQLTNAP QGGLAEFNPF SETNAATTVP VTQLPGSSQP 
61:	AVLQPSVEPT QPTPQAVVSA AQAGLLRQQE ELDRKAAELE RKERELQNTV ANLHVRQNNW 
121:	PPLPSWCPVK PCFYQDFSTE IPADYQRICK MLYYLWMLHS VTLFLNLLAC LAWFSGNSSK 
181:	GVDFGLSILW FLIFTPCAFL CWYRPIYKAF RSDNSFSFFV FFFVFFCQIG IYIIQLVGIP 
241:	GLGDSGWIAA LSTLDNHSLA ISVIMMVVAG FFTLCAVLSV FLLQRVHSLY RRTGASFQQA 
301:	QEEFSQGIFS SRTFHRAASS AAQGAFQGN