TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


8.A.117.1.2
Neuroligin-1, NGLN1, of 840 aas and 2 TMSs, N-terminal and near the C-terminus.  NGLN1 plays a role in memory by influencing synaptic transmission (Katzman and Alberini 2018).

Accession Number:Q8N2Q7
Protein Name:Neuroligin-1
Length:840
Molecular Weight:93835.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Cell membrane1 / Single-pass type I membrane protein2
Substrate

Cross database links:

Structure:
5OJ6   5OJK     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MALPRCTWPN YVWRAVMACL VHRGLGAPLT LCMLGCLLQA GHVLSQKLDD VDPLVATNFG 
61:	KIRGIKKELN NEILGPVIQF LGVPYAAPPT GERRFQPPEP PSPWSDIRNA TQFAPVCPQN 
121:	IIDGRLPEVM LPVWFTNNLD VVSSYVQDQS EDCLYLNIYV PTEDGPLTKK RDEATLNPPD 
181:	TDIRDSGGPK PVMVYIHGGS YMEGTGNLYD GSVLASYGNV IVITVNYRLG VLGFLSTGDQ 
241:	AAKGNYGLLD LIQALRWTSE NIGFFGGDPL RITVFGSGAG GSCVNLLTLS HYSEGNRWSN 
301:	STKGLFQRAI AQSGTALSSW AVSFQPAKYA RMLATKVGCN VSDTVELVEC LQKKPYKELV 
361:	DQDIQPARYH IAFGPVIDGD VIPDDPQILM EQGEFLNYDI MLGVNQGEGL KFVENIVDSD 
421:	DGISASDFDF AVSNFVDNLY GYPEGKDVLR ETIKFMYTDW ADRHNPETRR KTLLALFTDH 
481:	QWVAPAVATA DLHSNFGSPT YFYAFYHHCQ TDQVPAWADA AHGDEVPYVL GIPMIGPTEL 
541:	FPCNFSKNDV MLSAVVMTYW TNFAKTGDPN QPVPQDTKFI HTKPNRFEEV AWTRYSQKDQ 
601:	LYLHIGLKPR VKEHYRANKV NLWLELVPHL HNLNDISQYT STTTKVPSTD ITFRPTRKNS 
661:	VPVTSAFPTA KQDDPKQQPS PFSVDQRDYS TELSVTIAVG ASLLFLNILA FAALYYKKDK 
721:	RRHDVHRRCS PQRTTTNDLT HAQEEEIMSL QMKHTDLDHE CESIHPHEVV LRTACPPDYT 
781:	LAMRRSPDDV PLMTPNTITM IPNTIPGIQP LHTFNTFTGG QNNTLPHPHP HPHSHSTTRV