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8.A.16.2.2
Voltage-dependent Ca2+ channel γ3 subunit, CACNG3

Accession Number:O60359
Protein Name:CACNG3
Length:315
Molecular Weight:35549.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: O60359
eggNOG: prNOG04412
HEGENOM: HBG564649
RefSeq: NP_006530.1   
Entrez Gene ID: 10368   
Pfam: PF00822   
OMIM: 606403  gene
KEGG: hsa:10368   

Gene Ontology

GO:0030666 C:endocytic vesicle membrane
GO:0005891 C:voltage-gated calcium channel complex
GO:0005245 F:voltage-gated calcium channel activity
GO:0006816 P:calcium ion transport

References (3)

[1] “Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications.”  Black J.L. IIIet.al.   10221464
[2] “Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.”  Loftus B.J.et.al.   10493829
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRMCDRGIQM LITTVGAFAA FSLMTIAVGT DYWLYSRGVC RTKSTSDNET SRKNEEVMTH 
61:	SGLWRTCCLE GAFRGVCKKI DHFPEDADYE QDTAEYLLRA VRASSVFPIL SVTLLFFGGL 
121:	CVAASEFHRS RHNVILSAGI FFVSAGLSNI IGIIVYISAN AGDPGQRDSK KSYSYGWSFY 
181:	FGAFSFIIAE IVGVVAVHIY IEKHQQLRAK SHSEFLKKST FARLPPYRYR FRRRSSSRST 
241:	EPRSRDLSPI SKGFHTIPST DISMFTLSRD PSKITMGTLL NSDRDHAFLQ FHNSTPKEFK 
301:	ESLHNNPANR RTTPV