8.A.40.1.15 The tetraspan 24 protein, TSPAN24 or CD151 of 254 aas and 4 TMSs. Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. Also functions in egg-sperm interactions, possibly in cell-cell fusion, where oocyte CD151 interacts with CD49 in the sperm (Sabetian et al. 2014).
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Accession Number: | P48509 |
Protein Name: | CD151 antigen |
Length: | 253 |
Molecular Weight: | 28295.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 4 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
NONE |
---|
1: MGEFNEKKTT CGTVCLKYLL FTYNCCFWLA GLAVMAVGIW TLALKSDYIS LLASGTYLAT
61: AYILVVAGTV VMVTGVLGCC ATFKERRNLL RLYFILLLII FLLEIIAGIL AYAYYQQLNT
121: ELKENLKDTM TKRYHQPGHE AVTSAVDQLQ QEFHCCGSNN SQDWRDSEWI RSQEAGGRVV
181: PDSCCKTVVA LCGQRDHASN IYKVEGGCIT KLETFIQEHL RVIGAVGIGI ACVQVFGMIF
241: TCCLYRSLKL EHY