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8.A.95.1.1
Transmembrane and TPR repeat-containing protein, TMTC3, of 915 aas and 11 or 12 N-terminal TMSs with an extensive C-terminal hydrophilic domain including a tetratricopeptide (TPR) repeat-containing region.  It is involved in the ER stress response (Racapé et al. 2011) and co-localizes with the GABA transporter in pre-synaptic membranes and functions in the regulation of GABAergic inhibitory synapses (Farhan et al. 2017).

Accession Number:Q6ZXV5
Protein Name:Transmembrane and TPR repeat-containing protein 3
Length:915
Molecular Weight:104009.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MANINLKEIT LIVGVVTACY WNSLFCGFVF DDVSAILDNK DLHPSTPLKT LFQNDFWGTP 
61:	MSEERSHKSY RPLTVLTFRL NYLLSELKPM SYHLLNMIFH AVVSVIFLKV CKLFLDNKSS 
121:	VIASLLFAVH PIHTEAVTGV VGRAELLSSI FFLAAFLSYT RSKGPDNSII WTPIALTVFL 
181:	VAVATLCKEQ GITVVGICCV YEVFIAQGYT LPLLCTTAGQ FLRGKGSIPF SMLQTLVKLI 
241:	VLMFSTLLLV VIRVQVIQSQ LPVFTRFDNP AAVSPTPTRQ LTFNYLLPVN AWLLLNPSEL 
301:	CCDWTMGTIP LIESLLDIRN LATFTFFCFL GMLGVFSIRY SGDSSKTVLM ALCLMALPFI 
361:	PASNLFFPVG FVVAERVLYV PSMGFCILVA HGWQKISTKS VFKKLSWICL SMVILTHSLK 
421:	TFHRNWDWES EYTLFMSALK VNKNNAKLWN NVGHALENEK NFERALKYFL QATHVQPDDI 
481:	GAHMNVGRTY KNLNRTKEAE ESYMMAKSLM PQIIPGKKYA ARIAPNHLNV YINLANLIRA 
541:	NESRLEEADQ LYRQAISMRP DFKQAYISRG ELLLKMNKPL KAKEAYLKAL ELDRNNADLW 
601:	YNLAIVHIEL KEPNEALKKN FNRALELNPK HKLALFNSAI VMQESGEVKL RPEARKRLLS 
661:	YINEEPLDAN GYFNLGMLAM DDKKDNEAEI WMKKAIKLQA DFRSALFNLA LLYSQTAKEL 
721:	KALPILEELL RYYPDHIKGL ILKGDILMNQ KKDILGAKKC FERILEMDPS NVQGKHNLCV 
781:	VYFEEKDLLK AERCLLETLA LAPHEEYIQR HLNIVRDKIS SSSFIEPIFP TSKISSVEGK 
841:	KIPTESVKEI RGESRQTQIV KTSDNKSQSK SNKQLGKNGD EETPHKTTKD IKEIEKKRVA 
901:	ALKRLEEIER ILNGE