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8.B.10.1.1
Psalmotoxin-1 (PcTx1) 40 aas (Diochot et al., 2007).

Accession Number:P60514
Protein Name:PcTx1
Length:40
Molecular Weight:4695.00
Species:Psalmopoeus cambridgei [179874]
Location1 / Topology2 / Orientation3: Secreted1

Cross database links:

Gene Ontology

GO:0005576 C:extracellular region
GO:0019871 F:sodium channel inhibitor activity
GO:0009405 P:pathogenesis

References (2)

[1] “Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.”  Escoubas P.et.al.   10829030
[2] “Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels.”  Escoubas P.et.al.   12824480
Structure:
1LMM     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	EDCIPKWKGC VNRHGDCCEG LECWKRRRSF EVCVPKTPKT