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9.A.14.11.2
G-protein-coupled receptor, GPCR, family C, group 5 member C, isoform a

Accession Number:Q9NQ84
Protein Name:G-protein coupled receptor family C group 5 member C
Length:441
Molecular Weight:48193.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: Q9NQ84 Q9NQ84
eggNOG: NOG44972 NOG44972
HEGENOM: HOG000116197 HOG000116197
Entrez Gene ID: 55890   
Pfam: PF00003   
KEGG: hsa:55890    hsa:55890   

Gene Ontology

GO:0030659 C:cytoplasmic vesicle membrane
GO:0005887 C:integral to plasma membrane
GO:0004930 F:G-protein coupled receptor activity

References (20)

[1] “Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).”  Robbins M.J.et.al.   10945465
[2] “Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D.”  Braeuner-Osborne H.et.al.   11311935
[3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[4] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[5] “Human protein factory for converting the transcriptome into an in vitro-expressed proteome.”  Goshima N.et.al.   19054851
[6] “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.”  Zody M.C.et.al.   16625196
[7] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[8] “Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.”  Rikova K.et.al.   18083107
[9] “Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks.”  Wolf-Yadlin A.et.al.   17389395
[10] “ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.”  Matsuoka S.et.al.   17525332
[11] “Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).”  Robbins M.J.et.al.   10945465
[12] “Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D.”  Braeuner-Osborne H.et.al.   11311935
[13] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[14] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[15] “Human protein factory for converting the transcriptome into an in vitro-expressed proteome.”  Goshima N.et.al.   19054851
[16] “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.”  Zody M.C.et.al.   16625196
[17] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[18] “Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.”  Rikova K.et.al.   18083107
[19] “Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks.”  Wolf-Yadlin A.et.al.   17389395
[20] “ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.”  Matsuoka S.et.al.   17525332

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAIHKALVMC LGLPLFLFPG AWAQGHVPPG CSQGLNPLYY NLCDRSGAWG IVLEAVAGAG 
61:	IVTTFVLTII LVASLPFVQD TKKRSLLGTQ VFFLLGTLGL FCLVFACVVK PDFSTCASRR 
121:	FLFGVLFAIC FSCLAAHVFA LNFLARKNHG PRGWVIFTVA LLLTLVEVII NTEWLIITLV 
181:	RGSGEGGPQG NSSAGWAVAS PCAIANMDFV MALIYVMLLL LGAFLGAWPA LCGRYKRWRK 
241:	HGVFVLLTTA TSVAIWVVWI VMYTYGNKQH NSPTWDDPTL AIALAANAWA FVLFYVIPEV 
301:	SQVTKSSPEQ SYQGDMYPTR GVGYETILKE QKGQSMFVEN KAFSMDEPVA AKRPVSPYSG 
361:	YNGQLLTSVY QPTEMALMHK VPSEGAYDII LPRATANSQV MGSANSTLRA EDMYSAQSHQ 
421:	AATPPKDGKN SQVFRNPYVW D