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9.A.14.13.15
Chemokine-like receptor 1, Cmklr1, of 373 aas and 7 TMSs.  Receptor for the chemoattractant, adipokine chemerin/RARRES2, and for the omega-3 fatty acid-derived molecule, resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules leading to multifunctional effects, e.g., reduction of immune responses, enhancment of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages. Positively regulates adipogenesis and adipocyte metabolism (Krumm and Grisshammer 2015).

Accession Number:Q99788
Protein Name:Chemokine-like receptor 1
Length:373
Molecular Weight:42322.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NONE

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FASTA formatted sequence
1:	MRMEDEDYNT SISYGDEYPD YLDSIVVLED LSPLEARVTR IFLVVVYSIV CFLGILGNGL 
61:	VIIIATFKMK KTVNMVWFLN LAVADFLFNV FLPIHITYAA MDYHWVFGTA MCKISNFLLI 
121:	HNMFTSVFLL TIISSDRCIS VLLPVWSQNH RSVRLAYMAC MVIWVLAFFL SSPSLVFRDT 
181:	ANLHGKISCF NNFSLSTPGS SSWPTHSQMD PVGYSRHMVV TVTRFLCGFL VPVLIITACY 
241:	LTIVCKLQRN RLAKTKKPFK IIVTIIITFF LCWCPYHTLN LLELHHTAMP GSVFSLGLPL 
301:	ATALAIANSC MNPILYVFMG QDFKKFKVAL FSRLVNALSE DTGHSSYPSH RSFTKMSSMN 
361:	ERTSMNERET GML