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9.A.14.13.5
Leukotriene B4 receptor 1

Accession Number:Q15722
Protein Name:Leukotriene B4 receptor 1
Length:352
Molecular Weight:37557.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: Q15722 Q15722
eggNOG: NOG329990 NOG329990
HEGENOM: HBG445426 HBG445426
Entrez Gene ID: 1241   
Pfam: PF00001   
KEGG: hsa:1241    hsa:1241   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0000166 F:nucleotide binding
GO:0007200 P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0006928 P:cellular component movement
GO:0006955 P:immune response
GO:0006954 P:inflammatory response
GO:0006936 P:muscle contraction

References (14)

[1] “Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.”  Akbar G.K.M.et.al.   8702478
[2] “New members of the chemokine receptor gene family.”  Raport C.J.et.al.   8558062
[3] “A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.”  Yokomizo T.et.al.   9177352
[4] “Cloning of cDNA encoding a putative chemoattractant receptor.”  Owman C.S.O.et.al.   8921391
[5] “Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene.”  Kato K.et.al.   10934229
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[7] “Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.”  Gaudreau R.et.al.   12077128
[8] “Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.”  Akbar G.K.M.et.al.   8702478
[9] “New members of the chemokine receptor gene family.”  Raport C.J.et.al.   8558062
[10] “A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.”  Yokomizo T.et.al.   9177352
[11] “Cloning of cDNA encoding a putative chemoattractant receptor.”  Owman C.S.O.et.al.   8921391
[12] “Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene.”  Kato K.et.al.   10934229
[13] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[14] “Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.”  Gaudreau R.et.al.   12077128

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNTTSSAAPP SLGVEFISLL AIILLSVALA VGLPGNSFVV WSILKRMQKR SVTALMVLNL 
61:	ALADLAVLLT APFFLHFLAQ GTWSFGLAGC RLCHYVCGVS MYASVLLITA MSLDRSLAVA 
121:	RPFVSQKLRT KAMARRVLAG IWVLSFLLAT PVLAYRTVVP WKTNMSLCFP RYPSEGHRAF 
181:	HLIFEAVTGF LLPFLAVVAS YSDIGRRLQA RRFRRSRRTG RLVVLIILTF AAFWLPYHVV 
241:	NLAEAGRALA GQAAGLGLVG KRLSLARNVL IALAFLSSSV NPVLYACAGG GLLRSAGVGF 
301:	VAKLLEGTGS EASSTRRGGS LGQTARSGPA ALEPGPSESL TASSPLKLNE LN