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9.A.14.4.10
Secretin receptor

Accession Number:P47872
Protein Name:Secretin receptor
Length:440
Molecular Weight:50207.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: P47872
eggNOG: NOG244152
HEGENOM: HBG447108
Entrez Gene ID: 6344   
Pfam: PF00002    PF02793   
Drugbank: Drugbank Link   
KEGG: hsa:6344   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0015055 F:secretin receptor activity
GO:0007586 P:digestion
GO:0007588 P:excretion

References (4)

[1] “Molecular cloning and functional expression of a human pancreatic secretin receptor.”  Jiang S.et.al.   7864894
[2] “Molecular cloning and functional characterization of a human secretin receptor.”  Chow B.K.-C.et.al.   7612008
[3] “Molecular cloning and expression of a human secretin receptor.”  Patel D.R.et.al.   7700244
[4] “Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”  Hillier L.W.et.al.   15815621
Structure:
6WI9   6WZG     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MRPHLSPPLQ QLLLPVLLAC AAHSTGALPR LCDVLQVLWE EQDQCLQELS REQTGDLGTE 
61:	QPVPGCEGMW DNISCWPSSV PGRMVEVECP RFLRMLTSRN GSLFRNCTQD GWSETFPRPN 
121:	LACGVNVNDS SNEKRHSYLL KLKVMYTVGY SSSLVMLLVA LGILCAFRRL HCTRNYIHMH 
181:	LFVSFILRAL SNFIKDAVLF SSDDVTYCDA HRAGCKLVMV LFQYCIMANY SWLLVEGLYL 
241:	HTLLAISFFS ERKYLQGFVA FGWGSPAIFV ALWAIARHFL EDVGCWDINA NASIWWIIRG 
301:	PVILSILINF ILFINILRIL MRKLRTQETR GNEVSHYKRL ARSTLLLIPL FGIHYIVFAF 
361:	SPEDAMEIQL FFELALGSFQ GLVVAVLYCF LNGEVQLEVQ KKWQQWHLRE FPLHPVASFS 
421:	NSTKASHLEQ SQGTCRTSII