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9.A.5 The Putative Arginine Transporter (ArgW) Family

The putative arginine transporter (ArgW) of Shewanella oneidensis contains 452aas with 10 putative TMSs in a 4+2+4 arrangement and N- and C- termini predicted inside. The Geobacillus homologue, HisW, contains 441aas with 10 or 11 putative TMSs; both N- and C- termini are inside. It is called the COG3314 family or GATE Superfamily (Rodionov et al., 2009).

The reaction believed to be catalyzed by ArgW is:

arginine (out) → arginine (in)

This family belongs to the: Leucine-rich Repeat-containing Domain.

References associated with 9.A.5 family:

Ravcheev, D.A., A.A. Best, N. Tintle, M. Dejongh, A.L. Osterman, P.S. Novichkov, and D.A. Rodionov. (2011). Inference of the transcriptional regulatory network in Staphylococcus aureus by integration of experimental and genomics-based evidence. J. Bacteriol. 193: 3228-3240. 21531804
Rodionov, D.A., P. Hebbeln, A. Eudes, J. ter Beek, I.A. Rodionova, G.B. Erkens, D.J. Slotboom, M.S. Gelfand, A.L. Osterman, A.D. Hanson, and T. Eitinger. (2009). A novel class of modular transporters for vitamins in prokaryotes. J. Bacteriol. 191: 42-51. 18931129
Rodionov, D.A., P.S. Novichkov, E.D. Stavrovskaya, I.A. Rodionova, X. Li, M.D. Kazanov, D.A. Ravcheev, A.V. Gerasimova, A.E. Kazakov, G.Y. Kovaleva, E.A. Permina, O.N. Laikova, R. Overbeek, M.F. Romine, J.K. Fredrickson, A.P. Arkin, I. Dubchak, A.L. Osterman, and M.S. Gelfand. (2011). Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus. BMC Genomics 12Suppl1: S3. 21810205