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9.A.55.1.1
The probable cisplatin exporter, TMEM205. Genetic polymorphisms may alter chemotheraputic responses in lung cancer patients. (Shen et al., 2010; Shen and Gottesman 2012; Wang et al. 2014).  The N- and C-termini may be extracellular (Attwood et al. 2016).

Accession Number:Q6UW68
Protein Name:Transmembrane protein 205
Length:189
Molecular Weight:21198.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cisplatin

Cross database links:

Entrez Gene ID: 374882   
KEGG: hsa:374882   

Gene Ontology

GO:0016021 C:integral to membrane

References (4)

[1] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Lysine acetylation targets protein complexes and co-regulates major cellular functions.”  Choudhary C.et.al.   19608861

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MEEGGNLGGL IKMVHLLVLS GAWGMQMWVT FVSGFLLFRS LPRHTFGLVQ SKLFPFYFHI 
61:	SMGCAFINLC ILASQHAWAQ LTFWEASQLY LLFLSLTLAT VNARWLEPRT TAAMWALQTV 
121:	EKERGLGGEV PGSHQGPDPY RQLREKDPKY SALRQNFFRY HGLSSLCNLG CVLSNGLCLA 
181:	GLALEIRSL