9.B.186. The Putative Lipoprotein Supressor of a ts bamD mutant, YiaD (YiaD) Family
Tachikawa and Kato 2011 isolated temperature-sensitive mutants of the E. coli bamD gene, which is essential for the assembly of β-barrel outer membrane proteins. As their multicopy suppressor, they identified a novel yiaD gene encoding a putative lipoprotein, YiaD with 3 putative N-terminal TMSs and a C-terminal peptidoglycan-binding domain. Mutations of its OmpA domain, which is required for interaction with peptidoglycan, affected suppression, suggesting that interaction with peptidoglycan is important for YiaD function.