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9.B.214.1.2
Surfeit locus protein 4 of 269 aas and 8 predicted TMSs, Surf-4. It has amplification and increased expression in the tumor tissues of several human cancer patients. Overexpression of SURF4 led to increased cell proliferation, migration, and maintenance of anchorage-independent growth. In addition, NIH3T3 cells overexpressing SURF4 induced tumor growth in mice (Kim et al. 2018).

Accession Number:O15260
Protein Name:Surfeit locus protein 4
Length:269
Molecular Weight:30394.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate Unknown

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGQNDLMGTA EDFADQFLRV TKQYLPHVAR LCLISTFLED GIRMWFQWSE QRDYIDTTWN 
61:	CGYLLASSFV FLNLLGQLTG CVLVLSRNFV QYACFGLFGI IALQTIAYSI LWDLKFLMRN 
121:	LALGGGLLLL LAESRSEGKS MFAGVPTMRE SSPKQYMQLG GRVLLVLMFM TLLHFDASFF 
181:	SIVQNIVGTA LMILVAIGFK TKLAALTLVV WLFAINVYFN AFWTIPVYKP MHDFLKYDFF 
241:	QTMSVIGGLL LVVALGPGGV SMDEKKKEW