1.E.6 The T7 Holin (T7 Holin) Family

See 1.E for a generalized description of Holins.


This family belongs to the Holin Superfamily II.

 

References:

Lee, J.S., H.B. Jang, K.S. Kim, T.H. Kim, S.P. Im, S.W. Kim, J.M. Lazarte, J.S. Kim, and T.S. Jung. (2015). Complete Genomic and Lysis-Cassette Characterization of the Novel Phage, KBNP1315, which Infects Avian Pathogenic Escherichia coli (APEC). PLoS One 10: e0142504.

Nguyen, H.M. and C. Kang. (2014). Lysis Delay and Burst Shrinkage of Coliphage T7 by Deletion of Terminator T{varphi} Reversed by Deletion of Early Genes. J. Virol. 88: 2107-2115.

Summer, E.J., C.J. Enderle, S.J. Ahern, J.J. Gill, C.P. Torres, D.N. Appel, M.C. Black, R. Young, and C.F. Gonzalez. (2010). Genomic and biological analysis of phage Xfas53 and related prophages of Xylella fastidiosa. J. Bacteriol. 192: 179-190.

Xu, Y., Y. Ma, S. Yao, Z. Jiang, J. Pei, and C. Cheng. (2015). Characterization, Genome Sequence, and Analysis of Escherichia Phage CICC 80001, a Bacteriophage Infecting an Efficient L-Aspartic Acid Producing Escherichia coli. Food Environ Virol. [Epub: Ahead of Print]

Examples:

TC#NameOrganismal TypeExample
1.E.6.1.1

17.5 lysis protein, gb17.5 (67 aas); the phage T7 holin (Nguyen and Kang 2014).  This holin is 94% identical to the holin from E. coli phage CICC 80001 (Xu et al. 2015).

Proteobacterial phage T7

gb17.5 of E. coli phage T7

 
1.E.6.1.2

Putative lysis protein

Vibriophage

Putative lysis protein of Vibrio phage ICP3

 
1.E.6.1.3

Type II holin

Proteobacterial phage

Type II holin of Pseudomonas phage gh-1

 
Examples:

TC#NameOrganismal TypeExample
1.E.6.2.1

Putative holin

Proteobacterial viruses

Putative holin of Caulobacter phage Cd1

 
1.E.6.2.2

Putative holin-like phage protein

Proteobacteria

Putative holin-like phage protein of Candidatus Glomeribacter gigasporarum

 
1.E.6.2.3

Hypothetical protein

Proteobacteria

Hypothetical protein of Comamonas testosteroni

 
1.E.6.2.4

Putative class II holin

Proteobacterial phage

Class II holin of Enterbacterial phage LKA1

 
1.E.6.2.5

Holin of 77 aas and 1 central TMS from E. coli phage ECBP5, Orf46.  This protein is nearly identical to the pin-holin characterized for E. coli phage KBNP1315 (Lee et al. 2015).  It infects a pathogenic avian E. coli strain (Lee et al. 2015).

Holin of phage ICBP5 or KBNP1315.

 
1.E.6.2.6

Putative holin of 60 aas and 1 TMS

Holin of Pectobacterium phage PP1

 
1.E.6.2.7

Putative holin of 64 aas and 1 TMS

Holin of Lysobacter dokdonensis

 
Examples:

TC#NameOrganismal TypeExample
1.E.6.3.1

Phage pinholin (Summer et al. 2010).

Proteobacterial phage

Pinholin of Xyella phage Xfas53

 
1.E.6.3.2

putative pinholin

Proteobacteria

Pinholin of Stenophomonas maltophilia

 
1.E.6.3.3

Putatuve pinholin

Proteobacteria

Pinholin of Delftia acidovorans

 
1.E.6.3.4

Putative pinholin

Proteobacteria

Pinholin of Comamonas testosteroni

 
1.E.6.3.5

Putative pinholin

Proteobacteria

Pinholin of Laribacter honkongensis