3.D.14.1.1
This entry describes the HQNO-bound alternative complex III from the anoxygenic phototrophic bacterium Chloroflexus aurantiacus for which the structure has been determined at 1.9 Å resolution (Xin et al. 2024). A more detailed description is presented in the family description and especially by this reference. There are seven known subunites as follows: Subunits B, C, D, E, F, G, and I. They are to be found in NCBI under the general ID # 8X2J_ followed by the number of the subunit as indicated above. These subunits are:
B: 1029 aas and possibly 2 TMSs, 8X2J_B; FeS cluster-containing hydrogenase component-like protein
C: 486 aas and probably 10 TMSs, 8X2J_C: Polysulfide reductase, NrfD
D: 179 aas and 2 TMSs.
E: 205 aas and 1 N-terminal TMS
F: 411 aas and 10 TMSs. Subunits C and F are homologous, both with 10 TMSs, although they are distant in sequence.
G: 112 aas and 1 TMS
I: 37 aas and 1 TMS.
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| Accession Number: | 8X2J_B |
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| Protein Name: | B Chain B, Fe-S-cluster-containing hydrogenase components 1-like protein |
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| Length: | 1030 |
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| Molecular Weight: | |
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| Species: | Chloroflexus aurantiacus J-10-fl [324602] |
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| Number of TMSs: | 1 |
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| Substrate |
hydron |
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1: MTQQQPDLEA IRAQLRDARG PQFWRSLDQL ADAPAFRELI EREFPRGASE LEDGISRRTF
61: LKLMGASLAL AGVTACTYQP RQYIAPFDRQ PEGRVPGIPQ YFASTLTLGG YGTGVLVRSN
121: EGRPTKVEGN PRHPASLGGT DLFAQAEILT MYDPDRSTTV LRQGVPSTWA EFTTTLGNAL
181: TAARATQGAG VRLLTTTITS PSLAAQIEQF LQAYPQARWY QYEPINRDNV VAGARLAFGR
241: DVTTRYDLSA AQVVVSLDAD FLAPGPGFVA YARAFAERRK VRKDSTTMNR LYVVEASPST
301: TGTAADHRLP LRADAIAAFT GALANELGVG GAPATLSPKA EEFLRAIARD LEEHRGQSVV
361: IAGDQQPPIV HALAHLINAE LGNVGQTVFY HEPVEARPTN QTEELVALVS EMAAGRVETL
421: IMIGGNPVYN APGDLRFADR MASVPLTIHL SQFVDETSAR ATWHIPQAHP LESWGDARAF
481: DGTASIVQPL IEPLYGGKTA NELLAAMLGQ PEAESYDLVR SFWLEQIGET GWQVALANGV
541: IAETVAPVIE PTLNEGAIRA TPIPQPGDGV EIVFRPDPSL FDGFYANNGW LQELPRPLTK
601: LVWDNAALMS PRTAIKLLGL PFNADRLIGT EADDRERQQY LEQLSKVNGT IARIEYRGGI
661: IEIPIWLLPG HAEDSITLNL GYGRTHAGRV GNNVGIDVYP IRTSDSPWFG AGARVTNTGR
721: TYLLVSTQDH WTLEGRDIYR VGEFKKFKED PKYIAKEVYQ EEYGRETPNY QSLQPGDDYT
781: GRNAWGMTIN LNACIGCNAC VVACQAENNI AVVGKDQVSR GREMHWIRID RYFAGEDLDN
841: PSIYMMPVNC MQCEKAPCEV VCPVAATVHD YEGLNNMVYN RCVGTKYCSN NCPYKVRRFN
901: FLQYSDTTTE TFKLAFNPDV TVRIRGVMEK CTYCVQRISG ARIAAKRAAV QAGQSSYVIS
961: DGAIQTACEQ ACPTGAIVFG DINDSNSRVA KWKAEGHNYG LLGFLNTVPR TTYLARVRNP
1021: SEELEKVEG