3.A.1.27.7
Mce2A-F hetero-hexameric receptor complex of a lipid-transporting ABC uptake system. A Mycobacterium bovis Δmce2 double deletion mutant protects cattle against a challenge with virulent M. bovis (Blanco et al. 2013). The expression ratio of all selected mce operon genes in all M.
tuberculosis isolates was reduced at the initial phase and increased
substantially at a later phase of growth. Higher expression of mce1 operon genes was found in all M. tuberculosis isolates as compared to
other mce operon genes (mce2 and mce3 operons) at stationary growth
phase (Singh et al. 2016).
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| Accession Number: | A5TZX3 |
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| Protein Name: | MCE-family protein Mce2D |
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| Length: | 508 |
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| Molecular Weight: | 54540.00 |
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| Species: | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [419947] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MSTIFDIRSL RLPKLSAKVV VVGGLVVVLA VVAAAAGARL YRKLTTTTVV AYFSEALALY
61: PGDKVQIMGV RVGSIDKIEP AGDKMRVTLH YSNKYQVPAT ATASILNPSL VASRTIQLSP
121: PYTGGPVLQD GAVIPIERTQ VPVEWDQLRD SINGILRQLG PTERQPKGPF GDLIESAADN
181: LAGKGRQLNE TLNSLSQALT ALNEGRGDFV AITRSLALFV SALYQNDQQF VALNENLAEF
241: TDWFTKSDHD LADTVERIDD VLGTVRKFVS DNRSVLAADV NNLADATTTL VQPEPRDGLE
301: TALHVLPTYA SNFNNLYYPL HSSLVGQFVF PNFANPIQLI CSAIQAGSRL GYQESAELCA
361: QYLAPVLDAL KFNYLPFGSN PFSSAATLPK EVAYSEERLR PPPGYKDTTV PGIFSRDTPF
421: SHGNHEPGWV VAPGMQGMQV QPFTANMLTP ESLAELLGGP DIAPPPPGTN LPGPPNAYDE
481: SNPLPPPWYP QPASLPAAGA TGQPGPGQ