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2.A.6.2.16
Multidrug efflux pump, MexEF-OprN (exports fluoroquinolones, chloramphenicol, biocides, and xenobiotics; functions with MexE (MFP) and OprN (OMF)) as noted above (Kohler et al., 1997; Poole, 2008; Lorusso et al. 2022). The P. putida orthologue also exports solvents such as farnesyl hexanoate (Dunlop et al. 2011). MexAB-OprM is one of four primary drug exporters in P. aeruginosa (Lorusso et al. 2022).

Accession Number:A6V4W8
Protein Name:Outer membrane protein OprN
Length:472
Molecular Weight:51320.00
Species:Pseudomonas aeruginosa (strain PA7) [381754]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Lipid-anchor2
Substrate fluoroquinolone antibiotic, chloramphenicol, acrolein

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FASTA formatted sequence 
1:	MIHAQSIRSG LAPTLGLFSL LALSACTVGP DYRTPDTAAA KIDATASEPY DRSRFESLWW 
61:	KQFDDPTLNQ LVEQSLTGNR DLRVAFARLR AARALRDDVA NDRFPVVTSR ASADIGKGQQ 
121:	PGVTEDRVNS ERYDLGLDTA WELDLFGRIR RQLESSDALS EAAEADLQQL QVSLIAELVD 
181:	AYGQLRGAQL REKIALSNLE NQKESRQLTE QLRDAGVGAE LDVLRADARL AATAASVPQL 
241:	QAQAERSRHR IATLLGQRPE ELTVDLSPRD LPAISKALPI GDPGELLRRR PDIRAAERRL 
301:	ASSTAEVGVA TADLFPRVSL SGFLGFTAGR GSQIGSNAAR AWSVGPSISW AAFDLGSVRA 
361:	RLRGARADAD AALASYEQQV LLALEESANA FSDYGKRQER LVSLVRQSEA SRAAAQQAAI 
421:	RYREGTTDFL VLLDAEREQL SAEDAQAQAE VELYRGIVAI YRSLGGGWQP SA