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3.A.1.106.5
The heterodimeric multidrug efflux pump, SmdAB (exports norfloxacin, tetracycline, 4',6-diamidino-2-phenylindole (DAPI), and Hoechst 33342) (Matsuo et al., 2008).

Accession Number:A7VN01
Protein Name:SmdA
Length:591
Molecular Weight:65163.00
Species:Serratia marcescens [615]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate norfloxacin, tetracycline, DAPI, Hoechst 33342

Cross database links:

Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (1)

[1] “SmdAB, a heterodimeric ABC-Type multidrug efflux pump, in Serratia marcescens.”  Matsuo T.et.al.   18024518

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRLFAQIGWY FRREWRRYLG AVVLLIVIAI LQLLPPKLVG IIVDGVTEKQ MSTGVLMAWL 
61:	GLMIGTAIVV YLLRYVWRVL LFGASYQLAV ELRENFYRQL SRQNPAFYLR HRTGDLMARA 
121:	TNDVDRVVFA AGEGVLTLVD SLVMGLVVLV VMSTQISWQL TVLALIPMPL MAIAIKYYGD 
181:	QLHQRFKSAQ AAFSSLNDQA QESMTSIRMI KAFGLEDHQS NRFADVAAQT GAKNMHVARV 
241:	DARFDPTIYI AIGASNLLAI GGGSWMVVNG SLTLGQLTSF VMYLGLMIWP MLALAWMFNI 
301:	VERGSAAYSR IRSLLDEAPA VQDGPQALPA GRGVLDADIR AFHYPENPHP ALHDVALTLK 
361:	PGQMLGLCGP TGAGKSTLLS LIQRQFDVGQ GQIRYHGLPL PQVKLDDWRS RLSVVSQTPF 
421:	LFSDTVANNI ALGYPGATQA QIEQAARLAS VHEDILRLPQ GYDTEVGERG VMLSGGQKQR 
481:	ISIARALLLD AEILILDDAL SAVDGRTEHQ ILHNLRSWGQ DRTVIISAHR LSALTEAGEI 
541:	LVMQHGGVAQ RGDHAALAAQ PGWYRDMYRY QQLEAALDEA PENGEEALAD E