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| Accession Number: | A7VN01 |
| Protein Name: | SmdA |
| Length: | 591 |
| Molecular Weight: | 65163.00 |
| Species: | Serratia marcescens [615] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
| Substrate | 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole, norfloxacin, tetracycline, nifedipine |
Cross database links:
| Pfam: | PF00664 PF00005 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0055085
P:transmembrane transport
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References (1)[1] “SmdAB, a heterodimeric ABC-Type multidrug efflux pump, in Serratia marcescens.” Matsuo T.et.al. 18024518
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MRLFAQIGWY FRREWRRYLG AVVLLIVIAI LQLLPPKLVG IIVDGVTEKQ MSTGVLMAWL 61: GLMIGTAIVV YLLRYVWRVL LFGASYQLAV ELRENFYRQL SRQNPAFYLR HRTGDLMARA 121: TNDVDRVVFA AGEGVLTLVD SLVMGLVVLV VMSTQISWQL TVLALIPMPL MAIAIKYYGD 181: QLHQRFKSAQ AAFSSLNDQA QESMTSIRMI KAFGLEDHQS NRFADVAAQT GAKNMHVARV 241: DARFDPTIYI AIGASNLLAI GGGSWMVVNG SLTLGQLTSF VMYLGLMIWP MLALAWMFNI 301: VERGSAAYSR IRSLLDEAPA VQDGPQALPA GRGVLDADIR AFHYPENPHP ALHDVALTLK 361: PGQMLGLCGP TGAGKSTLLS LIQRQFDVGQ GQIRYHGLPL PQVKLDDWRS RLSVVSQTPF 421: LFSDTVANNI ALGYPGATQA QIEQAARLAS VHEDILRLPQ GYDTEVGERG VMLSGGQKQR 481: ISIARALLLD AEILILDDAL SAVDGRTEHQ ILHNLRSWGQ DRTVIISAHR LSALTEAGEI 541: LVMQHGGVAQ RGDHAALAAQ PGWYRDMYRY QQLEAALDEA PENGEEALAD E