2.A.6.1.15
The CzrCBA operon is induced by Cd2+ and Zn2+. CzrCBA transports Cd2+, Zn2+, and Co2+ but not Ni2+ (Valencia et al., 2013, in press).
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| Accession Number: | B8H146 |
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| Protein Name: | AcrB-family cation/multidrug efflux pump |
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| Length: | 1080 |
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| Molecular Weight: | 114861.00 |
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| Species: | Caulobacter crescentus (strain NA1000 / CB15N) [565050] |
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| Number of TMSs: | 9 |
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| Substrate |
cadmium(2+), cobalt(2+), zinc(2+) |
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1: MIGRILDLSV RARWAVIAVV ALVAALGVYN LIRLPIDAVP DITNKQVQIN TVVPALAPAE
61: VEKLVTFPVE TAMSGIPGLE STRSISRNGF SQVTIVFQEK TDLYFARQQV SERLTSVGKA
121: LPEGAQPAMG PISSGLGEVL MWTVAYDHPG GRGARVKDGA PGWQSDGAYL TITGERLTDT
181: TAQAAYLREV QDWIVRPQMR GVAGVAGVDS IGGYEKQFAV QPDPARMASY GVSFSQLAKA
241: LEAANIAVGA NFMERGGEAY LVRADARVRN IDEIANATVA TRAGMPIRVR DLATLKVGGG
301: LRTGAASENG EEVVVGTVLM LTGENSRAVA GASAERLKAI AKTLPPGVRV QITYDRSKLV
361: NATIKTVEKN LVEGALLVIA VLFVLLGNFR AALITALVIP LSMLMTAIGM NRLGVSGNLM
421: SLGALDFGLI VDGAVIIVEN SLRRLAERQH QEGRLLTSSE RLHETREAAR EMIAPTVYGQ
481: AIILLVYAPL LTFTGVEGKT FSPMAITVML ALAAAFVLSL TFIPAMVALL IRGKVAEKEV
541: ALVRWAKVGY APLLRKAVAR PWPVIAAATG LFVVAMITFT FLGREFTPQL DEKDLAVQAL
601: RIPSTSLEQS LRMQRQIERT IAAFPEVEFV YSKTGTAEVA SDPMPPNASD SFIILKAQDE
661: WPDSKQSKAQ LVDRMERKLE GLTGNVYEFS QPIQMRFNEL IAGVRGDVAI KVYGDDLAAM
721: TASADQIAGV LRGVRGAADV KVEQTSGFPT LDVSLDRDAI GRLGLTVEEV ADTLAVAMGG
781: RASGLVFQGD RRFEVVVRLP EATRNDLDAI GALPVMLPHG ASAGPRLSVP LRDVARFSFS
841: EGLNQVSREN GKRRVVVQAN VRGNDLGSFV SEAQAKVSAQ IELPAGSWVE WSGQFENLKA
901: AQSRLSLVVP LCFLLIFALL YMALGGFAPA LAVFSAIPLA LAGGVFGLAL RGIPFSVSAA
961: VGFIALSGVA VLNGLVMMTA IRQRLAQGLA LEQAIIAGAM ERLRPVMMTG LVASLGFVPM
1021: ALATETGAEV QRPLATVVIG GLITATALTL FVLPAICRFV LRQAPKATPE PAAPPQEQGA