3.A.2.1.9 Sodium (Na+)-pumping F-type ATPase. ATPase activity is stimulated by Na+ (Wiangnon et al. 2007), and Na+ transport in liposomes has been demostrated (Soontharapirakkul and Incharoensakdi 2010). The enzyme appears to play a role in salt tolerance (Soontharapirakkul et al. 2011). This halotolerant cyanobacterium has both a Na+- and a H+-pumping ATPase (see TC# 3.A.2.1.10). The sequence of the δ-subunit was not available at the time of entry. The phototroph-specific beta-hairpin structure of the gamma subunit of FoF1-ATP synthase is important for efficient ATP synthesis in cyanobacteria (Kondo et al. 2021). ATP is an inhibitor of the F0F1-ATP synthase to arrest ATP hydrolysis during low-energy conditions in cyanobacteria (Song et al. 2022).
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Accession Number: | BAK19938 |
Protein Name: | BAK19938.1 ApNa+ATPase alpha subunit [Aphanothece halophytica] |
Length: | 515 |
Molecular Weight: | |
Species: | Aphanothece halophytica [72020] |
Substrate |
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1: MNEDNHPLTH LVETTFSQWE SVLDQYRFPL QAHEVGIVKS VSSGIATVSG LFGARLDELI
61: EFPEGLLGIA FNLDAEEIGV ILLGDSEGVQ AGDKVYRLGR ILDVPVGEAL LGRVVDGLGR
121: PLDNKGEIET SERLPTERPA RGIMERAPVE VPLQTGIKVI DALIPVGRGQ RELIVGDRQI
181: GKTAIAVDTI LNQKQHNVIC IYCAIAQRGA AVAKVIDRLR QHQAMDYTVV VVAPGESPPG
241: LKYITPYAAT SIGEYFRDQG RDVLIIYDDL TQHAWAYREL SLLLRRPPGR EAYPGDIFYI
301: HSRLLERATH LRDELGGGSL TALPLVETQA QNISAYIPTN LISITDGQIY LSPNLFQQGI
361: LPAVDVGKSV SRVGGKTQLP AYRRVSSDLR LSYSQFQEVE VFARFGTRLD EQTRHTLERG
421: RRVREVLKQK ESKSLTPAEQ VAILFAVNNG LFDEIPLDQI KTAEARVQAV MNGELSQLRD
481: QIQNGEKLSE EDIDTLSQAL KNTTTQLQEE IRHD