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2.A.63.2.1 The Na⁺:H⁺antiporter, MrpA-G complex. Catalyzes Na⁺:H⁺and Li⁺:H⁺ antiport. The MrpB subunit may have this transport activity by itself (Fukaya et al., 2009).
Accession Number:	C7G3J0
Protein Name:	Multiple resistance and pH regulation
Length:	483
Molecular Weight:	53212.00
Species:	Aphanothece halophytica [72020]
Number of TMSs:	16
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	lithium(1+), sodium(1+), hydron

Pfam:	PF00361
Gene Ontology GO:0008137 F:NADH dehydrogenase (ubiquinone) activity GO:0048038 F:quinone binding GO:0042773 P:ATP synthesis coupled electron transport
References (1) [1] “An Mrp-like cluster in the halotolerant cyanobacterium Aphanothece halophytica functions as a Na+/H+ antiporter.” Fukaya F.et.al. 19700555

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MMQLTIVWIA LSFFVGFVIY LVPNLSRWLA LVVAFTSLAY SGFLFLQPSA INIQLLDSFG 
61:	VTLIADQLSS FFILTNALVT IALIFYCWQS EKPSFFFMQL VILHGSVNAT FICADLISLY 
121:	VALEVISIAA FLLISYPRSD RVVWVGLRYL FVSNTAMLFY LVGTILVYQV NHSFSFAGLQ 
181:	NSPPDAIALI FLGLLVKGGI FFSGLWLPLT HSESESPVSA MLSGVVVKAG VFPLVRLALM 
241:	IDTVDPIVRF FGVGTALLGV AYAIFEKDTK RTLAFSTISQ LGFIVAAPAV GGFYALTHGL 
301:	VKSALFLIAG NLPSRDFKQL QDHPIPTEIW ITLVIAGFSI SGFPLLSGFG AKVLTSKNLL 
361:	PWQVVAMNLA AFGTAITLGK FIFLPHQRIS QSNVKLGFWL AMFILLGGLV AANVFYYEAY 
421:	TLENILKPLA IIALGWLTYL LLIKKVIIQL PRNLEKFDHL VGGMPLMLIL LFWSVWTKSS 
481:	ILK

2.A.63.2.1
The Na⁺:H⁺antiporter, MrpA-G complex. Catalyzes Na⁺:H⁺and Li⁺:H⁺ antiport. The MrpB subunit may have this transport activity by itself (Fukaya et al., 2009).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.63.2.1The Na+:H+ antiporter, MrpA-G complex. Catalyzes Na+:H+ and Li+:H+ antiport. The MrpB subunit may have this transport activity by itself (Fukaya et al., 2009).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.63.2.1
The Na⁺:H⁺antiporter, MrpA-G complex. Catalyzes Na⁺:H⁺and Li⁺:H⁺ antiport. The MrpB subunit may have this transport activity by itself (Fukaya et al., 2009).