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3.A.1.105.26
Putative ABC transporter with two membrane proteins, both with 6 TMSs, one with them in a 2 + 2 + 2 TMS arrangement, the other in a 2 + 3 + 1 TMS arrangement. The two genes encoding these proteins are next to each other on the chromosome.  The ATPase is fused to the first of these two membrane protein domains (acc # C7QI22). These two genes, presumable encoding an ABC exporter, are adjacent to lantibiotic biosynthesis genes. Therefore their function may be to export a lantibiotic. The N-terminal hydrophilic domain of C7QI22 is an S2P-M50-like peptidase (TC# 9.B.149) that may process the pro-lantibiotic during export.

Accession Number:C7QI21
Protein Name:Transport permease protein
Length:258
Molecular Weight:27072.00
Species:Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) [479433]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

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FASTA formatted sequence
1:	MSAGNPNASG TPLGALSVAI ARSYYRDKVT LFFTFAFPLI FLVVFGVLFR DQTVGGGGFI 
61:	ASTAAGVLSW AVATSALFGV AYTLMHWRST EVLRVIRMTP TRLPTVMGSR FLVAVAVALV 
121:	QAVFFVGVAM LPVFGLRLSG RAVLAIPAIL AGVTAFFALG LLVSVVASSS EAIAAIANCV 
181:	MTPMAFLSGT FYPISLSPRW IQDVSWVLPL RYLVNGTVGP VGGTGGISTV LVSCAALLGF 
241:	TALFAGLAAR YFRWSREA