2.A.6.2.43
Multidrug resistance pump, SmeJK. Shown to export teracycline, minocycline, ciprofloxacin and levofloxacin (Gould et al., 2012).
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| Accession Number: | I0KTJ0 |
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| Protein Name: | Acriflavin resistance plasma membrane protein |
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| Length: | 1077 |
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| Molecular Weight: | 115418.00 |
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| Species: | Stenotrophomonas maltophilia D457 [1163399] |
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| Number of TMSs: | 12 |
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| Substrate |
levofloxacin, ciprofloxacin, minocycline, tetracycline |
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1: MGFSTIFIRR PIATSLLMAG LLLLGILGYR KLPVSALPEI DAPSLVVTTQ YPGANATTMA
61: SLVTTPLERQ FGQISGLELM TSDSSAGLST IILQFSMDRD IDIAAQDVQA AIRQATLPSS
121: LPYQPVYNRV NPADAAIVTL KLTSDTRPLR DVNNYADSIL AQRLSQVQGV GLVSIAGNVR
181: PAVRIQVNPA QLSNMGLTLE QLRSALTQAN VNAPKGSLNG KTQSYSIGTN DQLASAAEYR
241: DTIISYKNGR PVRLSDVAEV IDGVENDQLA AWADGKPAVL LEVRRQPGAN IVQTVERIRA
301: ILPQLQGVLP ADVHLEIFND RTETIRASVH EVQFTLILTI GLVVAVIFVF LRRLWATIIP
361: SVAVPLSLAG TFAVMAFAGM SLDNLSLMAL VVATGFVVDD AIVMIENIVR YIEQGKSGKE
421: AAEIGARQIG FTVLSLTVSL VAVFLPLLLM PGVTGRLFHE FAWVLSIAVV LSMLISLTLT
481: PMMCAYLLKP DALPEGEDAH ERAAAAGKQN LWTRTVGLYE HSLDWVLDHQ RLTLAVAGGA
541: LVLTVLLYVL IPKGLLPEQD TGLITGVVQA DQNIAFPQME QRTKQVAEAL RHDPDVTGVS
601: AFIGAGSMNP TLNQGQLSIV LKERSQRDGL EQILPRLQKA VAGIPGVALY LKPVQDVTLD
661: TRVAATEYQY SLSDVDSATV ATQATRLTEA LRKRPELADV DNNLSNQGRA LELNIDRDKA
721: SVLGVPMQTI DDTLYDAFGQ RQISTIFTEL NQYRVVLEVA PEFRTSTALM EQLAVASNGA
781: GALTGTNATS FGQVTSSNSS TATGIGAQNT GITVGAGNII PLSALAEGKV SSAPLVVSHQ
841: QQLPAVTVSF NVAPGYSLSE AVRAIQETKD SLDMPTHLHA EFIGKAAEFT GSQTDVVWLL
901: LASLVVIYIV LGVLYESYIH PITIISTLPP AGVGALLALM LCGLSLSVDG IVGIVLLIGI
961: VKKNGIMMVD FAIEARRAGA NAHEAIRRAC LLRFRPIMMT TAAAMLGALP LALGTGIGSE
1021: LRRPLGIAIV GGLLLSQLVT LYTTPVIYLY MERFSEWLAR RREQRALRDG SLQEPQA