2.A.54.1.14
Sideroflexin 3 (SFXN3) with 308 aas and 4 putative C-terminal TMSs. It may form a complex with poly(rC)-binding protein-2, PCBP2 (335 aas and possibly 4 N-terminal TMSs; AAI07689.1) and TOM20 (145 aas and possibly 1 N-terminal TMS; NP_055580.1) (Mi et al. 2024). This complex may serve as an iron entry pathway into mitochondria (Mi et al. 2024).
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| Accession Number: | NP_001374961.1 |
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| Protein Name: | NP_001374961.1 sideroflexin-3 isoform 3 [Homo sapiens] |
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| Length: | 309 |
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| Molecular Weight: | |
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| Species: | Homo sapiens [9606] |
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| Number of TMSs: | 4 |
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| Substrate |
iron(2+) |
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1: MESKMGELPL DINIQEPRWD QSTFLGRARH FFTVTDPRNL LLSGAQLEAS RNIVQNYRAG
61: VVTPGITEDQ LWRAKYVYDS AFHPDTGEKV VLIGRMSAQT PTVVFWQWVN QSFNAIVNYS
121: NRSGDTPITV RQLGTAYVSA TTGAVATALG LKSLTKHLPP LVGRFVPFAA VAAANCINIP
181: LMRQRELQVG IPVADEAGQR LGYSVTAAKQ GIFQVVISRI CMAIPAMAIP PLIMDTLEKK
241: DFLKRRPWLG APLQVGLVGF CLVFATPLCC ALFPQKSSIH ISNLEPELRA QIHEQNPSVE
301: VVYYNKGL