3.A.1.27.5 The Mce/Yrb/Mlk (Mammalian cell entry) ABC-type putative steroid uptake transporter (involved in several aspects of mycobacterial pathogenesis) (Mohn et al., 2008; Joshi et al., 2006).
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Accession Number: | O06356 |
Protein Name: | CONSERVED HYPOTHETICAL MCE ASSOCIATED ALANINE AND VALINE RICH PROTEIN |
Length: | 242 |
Molecular Weight: | 25611.00 |
Species: | mycobacterium tuberculosis [1773] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate |
steroid |
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RefSeq: |
NP_218010.1
NP_338142.1
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Entrez Gene ID: |
888379
926596
|
KEGG: |
mtc:MT3597
mtu:Rv3493c
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[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T. et.al. 9634230
[2] “Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv.” Camus J.-C. et.al. 12368430
[3] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.” Fleischmann R.D. et.al. 12218036
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1: MAADTGVAGG QQSTTRRARR KASRPAGPAE GESSRPAQGA ATVRAAARTE SKPAKAAKPA
61: LRPVKPPPRR PAHRVLVGWL SLAAGLLAIA ALAWGVTALV MQNRDADARQ ARNQRFVDAA
121: TQTVVNMFSY TPDTIDESVN RFVNGTSGPL RGMLNANNNV DNLKGLFRAT NATSEAVVNG
181: AALEGIDEIS DNASVLVSVR VTVADIDGVN KPSMPYRLRV IVHEDENGRM TGYDLKYPDG
241: GN