3.A.1.27.7
Mce2A-F hetero-hexameric receptor complex of a lipid-transporting ABC uptake system. A Mycobacterium bovis Δmce2 double deletion mutant protects cattle against a challenge with virulent M. bovis (Blanco et al. 2013). The expression ratio of all selected mce operon genes in all M.
tuberculosis isolates was reduced at the initial phase and increased
substantially at a later phase of growth. Higher expression of mce1 operon genes was found in all M. tuberculosis isolates as compared to
other mce operon genes (mce2 and mce3 operons) at stationary growth
phase (Singh et al. 2016).
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| Accession Number: | O07784 |
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| Protein Name: | Mce-family protein Mce2F |
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| Length: | 516 |
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| Molecular Weight: | 54194.00 |
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| Species: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MLTRAIKTQL VLLTVLAVIA VVVLGWYFLR IPSLVGIGRY TLYAELPRSG GLYRTANVTY
61: RGITIGKVTG VEPTERGARA TMSIDNGYQI PTDASANVHS VSAVGEQFVD LVSTRTSGPY
121: LRHGQTITTT TVPSQIGPAL DAANRGLAVL PKDRVASVLH EASEAVGGLG SSLNRLIEAT
181: QAIAHDVRGS LEDIDDIIER SAPIIDSQVN SGNEIARWAA NLNTLAAQTA QTDPAVRSIL
241: ANAAPTADQV NATFSDVRES LPQTLANLEV VIDMLKRYHN GVEQALVFLP QSGAIAQSVT
301: TEFPGQAGLG VGGLALNQPP PCLTGFLPAS EWRSPADTST APLPKGTYCR IPMDASNVVR
361: GARNNPCVDV PGKRAATPRE CRSNEAYVPG GTNPWYGDPN QMLSCPAPAA RCDQPVKPGQ
421: VIPAPSVNNG INPLPADQLP GTPPPVNDPL QRPGSGTVQC NGQQPNPCVY TPSTFPTTIY
481: DVQSGKVVAP DGVVYSVEAS THAGADGWKV MLAPTG