3.A.1.27.7
Mce2A-F hetero-hexameric receptor complex of a lipid-transporting ABC uptake system. A Mycobacterium bovis Δmce2 double deletion mutant protects cattle against a challenge with virulent M. bovis (Blanco et al. 2013). The expression ratio of all selected mce operon genes in all M.
tuberculosis isolates was reduced at the initial phase and increased
substantially at a later phase of growth. Higher expression of mce1 operon genes was found in all M. tuberculosis isolates as compared to
other mce operon genes (mce2 and mce3 operons) at stationary growth
phase (Singh et al. 2016).
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| Accession Number: | O07787 |
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| Protein Name: | Mce-family protein Mce2C |
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| Length: | 481 |
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| Molecular Weight: | 50764.00 |
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| Species: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332] |
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| Number of TMSs: | 2 |
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| Substrate |
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1: MRTLTEFNRG RVGMMGAVVT VLVVGVAQSF TSVPMLFATP TYYAQFADTG GINTGDKVEI
61: AGVNVGLVRS LAIRGNRVLI GFSLPGKTIG MQSRAAIRTD TILGRKNLEI EPRGSEPLKP
121: NGFLPLAQTT TPYQIYDAFV DVTKAATGWD IDAVKRSLNV LSETFDQTAP HLSAALEGVK
181: AFSDTVGRRG EQIEQLLANA NRIARVLGDR SEQVNGLLVN AKTLLAAFKQ RSQALRILLT
241: NVSEASAQVS GLITDNPNLN HVLAQLRTVS EELVKRKNEL ADVAVLLGRY TAALTEAVGS
301: GPFFKAMVVN LLPYQILQPW VDAAFKKRGI DPENFWRSAG LPEFRWPDPN GTRFPNGAPP
361: AAPPVREGTP KHPGPAVPPG TPCSYTPAAG ALPRPDTPLP CAGATVGPFG GPDFPAPLDV
421: QPSPPNPDGP PPTPGILSAG RPGEPAPAVP GIPMPLPPNA PPGARTQPLE PFPDGTGGSN
481: Q