8.A.54.1.8
Alpha 5 integrin of 1049 aas and 2 TMSs, N- and C-terminal. It forms a dimer with the Beta1 integrin of 200 aas and 0 TMSs. This essential heterodimeric transmembrane protein mediates the communication between the extracellular matrix and the cytosolic cytoskeleton in processes of cell adhesion and migration (Dransart et al. 2022).
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| Accession Number: | O14713 |
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| Protein Name: | Integrin beta-1-binding protein 1 |
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| Length: | 200 |
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| Molecular Weight: | 21782.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Nucleus1 |
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| Substrate |
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1: MFRKGKKRHS SSSSQSSEIS TKSKSVDSSL GGLSRSSTVA SLDTDSTKSS GQSNNNSDTC
61: AEFRIKYVGA IEKLKLSEGK GLEGPLDLIN YIDVAQQDGK LPFVPPEEEF IMGVSKYGIK
121: VSTSDQYDVL HRHALYLIIR MVCYDDGLGA GKSLLALKTT DASNEEYSLW VYQCNSLEQA
181: QAICKVLSTA FDSVLTSEKP