1.C.36.2.2
IIITCP protein complex, PopB/PopD. Purified PopB and PopD form pores in model membranes (Romano et al., 2011). PopB in isolation forms a biimodal distribution of two complexes with 6 and 12 subunits while PopD forms a hexameric complex. However when present together, they form a hexadecameric transmembrane complex (Romano et al. 2016). PopB assists with the proper insertion of PopD into cell membranes and is required for the formation of a functional translocon and host infection (Tang et al. 2018).
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| Accession Number: | O30529 |
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| Protein Name: | PopB |
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| Length: | 392 |
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| Molecular Weight: | 40277.00 |
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| Species: | Pseudomonas aeruginosa [287] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
protein |
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[1] “Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.” Yahr T.L. et.al. 9371466
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1: MNPITLERAG LPYGVADAGD IPALGRPVAR DVESLRVERL AAPAAASASG TGVALTPPSA
61: ASQQRLEVAN RAEIASLVQA VGEDVGLARQ VVLAGASTLL SAGLMSPQAF EIELAKITGE
121: VENQQKKLKL TEIEQARKQN LQKMEDNQQK IRESEEAAKE AQKSGLAAKI FGWISAIASI
181: IVGAIMVATG VGAAAGALMI AGGVMGVVSQ SVQQAAADGL ISKEVMEKLG PALMGIEIAV
241: ALLAAVVSFG GSAVGGLARL GAKIGGKAAE MTASLASKVA DLGGKFGSLA GQSLSHSLKL
301: GVQVSDLTLD VANGAAQATH SGFQAKAANR QADVQESRAD LTTLQGVIER LKEELSRMCM
361: LEAFQEIMER IFAMLQAKGE TLHNLSSRPA AI