3.A.1.122.2
The SpdC antimicrobial peptide resistance efflux pump, YknXYZ (Butcher and Helmann, 2006). YknW (TC# 9.B.29.2.17), a 5 TMS protein, interacts directly with YknXYZ and is essential for facilitation of its assembly, thus serving as an integral membrane chaparone (Yamada et al., 2012). The MFP YknX requires the ATP-binding cassette (ABC) transporter YknYZ
and the Yip1 family protein YknW to form a functional complex. YknX (MFP) is hexameric (Xu et al. 2017).
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| Accession Number: | O31710 |
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| Protein Name: | Putative efflux system component yknX |
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| Length: | 377 |
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| Molecular Weight: | 41707.00 |
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| Species: | Bacillus subtilis (strain 168) [224308] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass membrane protein2 |
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| Substrate |
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| Entrez Gene ID: |
938774
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| KEGG: |
bsu:BSU14350
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[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F. et.al. 9384377
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1: MKKVWIGIGI AVIVALFVGI NIYRSAAPTS GSAGKEVQTG SVEENEISST VMVPGTLKFS
61: NEQYVFYEAD KGTLEDIKVK EGDKVKKGTA LVTYTNEQLS LEKEQNQLTS ESNRLQIDQI
121: QEKLKALDSK ERELEKQVGK KEAEKQIESE RTELQMQKKT AEIELKQTEL QRQSLANRVS
181: DLEVKSEIEG TVISVNQEAA SKKSDIQEPV IHIGNPKDLV VSGKLSEYDT LKVKKGQKVT
241: LTSDVIQGKT WKGTVSAVGL VPDQQESAAA QGTEQAVQYP LQVKIKGNLP EGKPGFKFIM
301: NIETDKRKAN TLPSKAVKKE DDQYYVYTVK DGKAKRVDVK IGEVTDDLTE IKEGLTQDDQ
361: VILNPSDQVT DGMEVKS