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2.A.38.4.3
Low affinity (1 mM) K+ uptake transporter, KtrAB. Evidence for structural similarities between potassium channels and KtrB proteins in the extracellular half of the molecule and differences in the cytoplasmic regions has been obtained (Albright et al., 2007). This system is responsible for K+ accumulation in the cell cytoplasm, allowing oscillatory release of K+ from a biofilm through the BikC (YugO) K+ channel for the attraction of other bacteria (both of the same and different species) to the biofilm (Humphries et al. 2017).

Accession Number:O32081
Protein Name:KtrB aka YubG
Length:445
Molecular Weight:48437.00
Species:Bacillus subtilis [1423]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate potassium(1+)

Cross database links:

RefSeq: NP_390988.1   
Entrez Gene ID: 938835   
Pfam: PF02386   
BioCyc: SUBTI:BSU31100-MONOMER   
KEGG: bsu:BSU31100   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008324 F:cation transmembrane transporter activity
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (4)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “KtrAB and KtrCD: two K+ uptake systems in Bacillus subtilis and their role in adaptation to hypertonicity.”  Holtmann G.et.al.   12562800
[3] “The RCK domain of the KtrAB K+ transporter: multiple conformations of an octameric ring.”  Albright R.A.et.al.   16990138
[4] “Probing the structure of the dimeric KtrB membrane protein.”  Albright R.A.et.al.   17932047
Structure:
4J7C   5but     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLQKDKVIK WVRFTPPQVL AIGFFLTIII GAVLLMLPIS TTKPLSWIDA LFTAASATTV 
61:	TGLAVVDTGT QFTVFGQTVI MGLIQIGGLG FMTFAVLIVM ILGKKIGLKE RMLVQEALNQ 
121:	PTIGGVIGLV KVLFLFSISI ELIAALILSI RLVPQYGWSS GLFASLFHAI SAFNNAGFSL 
181:	WPDNLMSYVG DPTVNLVITF LFITGGIGFT VLFDVMKNRR FKTFSLHTKL MLTGTLMLNA 
241:	IAMLTVFILE YSNPGTLGHL HIVDKLWASY FQAVTPRTAG FNSLDFGSMR EGTIVFTLLL 
301:	MFIGAGSAST ASGIKLTTFI VILTSVIAYL RGKKETVIFR RSIKYPIIIK ALAVSVTSLF 
361:	IVFLGIFALT ITEQAPFLQI VFETFSAFGT VGLTMGLTPE LTTAGKCIII VIMFIGRIGP 
421:	LTFVFSFAKT EQSNIRYPDG EVFTG