3.A.1.122.19 ABC3-type efflux porter, YtrEF, encoded within an operon, ytrABCDEF, apparently encoding two ABC exporters, one, YtrBCD, with TC# 3.A.1.153.1, and the other, this one. The operon is induced in early stationary phase under the control of YtrA, a GntR-type HTH transcriptional regulator, probably a repressor (Yoshida et al. 2000). These authors suggest this operon may be involve in acetoin secretion and/or reutilization, but it has also been suggested that it also plays a role in peptidoglycan (cell wall) biogenesis (Rismondo and Schulz 2021).
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Accession Number: | O34392 |
Protein Name: | ABC transporter ATP-binding protein YtrE |
Length: | 231 |
Molecular Weight: | 25460.00 |
Species: | Bacillus subtilis (strain 168) [224308] |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Peripheral membrane protein2 / Cytoplasmic side3 |
Substrate |
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1: MIDVQHIDHS FTIGKKGREN EVPVLKDVSL SVAKGEIACI VGRSGSGKST LLNLISGYIS
61: PTKGRIVING TDVTGFNEKE WAQFRLDHFG FIFQSFQLIP GLTTYENVEM PLALKGIKPS
121: ERKQKVQDML KRVGLENHAA HYPNELSGGQ QQRVSIARAL ILNPSIILAD EPTGSLDSET
181: EHEVLELIQQ LNRERGITFV IITHDDEVAS IGHSKFQLHD GVLKGGITVE V