TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.153.1
ABC transporter complex YtrBCD that may play a role in acetoin utilization during stationary phase and sporulation (Yoshida et al. 2000). Expression is induced early in the stationary phase. The six ytr genes form a single operon, transcribed from a promoter present upstream of ytrA. YtrA, which possesses a helix-turn-helix motif of the GntR family, may be a repressor that regulates its own transcription as well as the whole operon. Inactivation of the operon led to a decrease in the maximal cell yield and less-efficient sporulation. B. subtilis produces acetoin as an external carbon storage compound and then reuses it later during stationary phase and sporulation. Possibly the Ytr porter plays a role (Yoshida et al. 2000). It may also play a role in peptidoglycan (cell wall) synthesis. (Rismondo and Schulz 2021). The YtrEF system, believed to be a distinct ABC efflux system (M. Saier, unpublished results), can be found under TC# 3.A.1.122.19.

Accession Number:O34898
Protein Name:Probable ABC transporter permease YtrC
Length:328
Molecular Weight:36951.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MVDRGLLYRE WKQNQVVILL SIAFLVLANP LSIVNTYLSY QGCLDRQDPQ YCDFIVNYSI 
61:	SNLIDINWVP GVILAVCFLG MERSKGTMDF ILSLPYNRSQ IFQTKFWLGG FVIVLSQLIG 
121:	FLLAWLLILV YNPEHVYFFE HSSIGVIVIS FMAFSLVMAA GALTGNAFAQ LLTAFSAAIL 
181:	PYLIIALPVG NLEVVFGANI WEIFPSPESY FSLASNLSNL VPISYVVNEW LINSKYLLLI 
241:	PAVMSMLFYL IGFISFKKLP SERNGHFFLW NRLDRPVQIL VMAFGILGFG LFGYYTGHSI 
301:	IGYILGMIIG AVAGFFVSYF SIYKKTKV