3.A.1.153.1 ABC transporter complex YtrBCD that may play a role in acetoin utilization during stationary phase and sporulation (Yoshida et al. 2000). Expression is induced early in the stationary phase. The six ytr genes form a single operon, transcribed from a promoter present upstream of ytrA. YtrA, which
possesses a helix-turn-helix motif of the GntR family, may be a
repressor that regulates its own transcription as well as the whole operon. Inactivation of the
operon led to a decrease in the maximal cell yield and less-efficient
sporulation. B. subtilis produces acetoin as
an external carbon storage compound and then reuses it later during
stationary phase and sporulation. Possibly the Ytr porter plays a role (Yoshida et al. 2000). It may also play a role in peptidoglycan (cell wall) synthesis. (Rismondo and Schulz 2021). The YtrEF system, believed to be a distinct ABC efflux system (M. Saier, unpublished results), can be found under TC# 3.A.1.122.19.
|
Accession Number: | O34898 |
Protein Name: | Probable ABC transporter permease YtrC |
Length: | 328 |
Molecular Weight: | 36951.00 |
Species: | Bacillus subtilis (strain 168) [224308] |
Number of TMSs: | 8 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MVDRGLLYRE WKQNQVVILL SIAFLVLANP LSIVNTYLSY QGCLDRQDPQ YCDFIVNYSI
61: SNLIDINWVP GVILAVCFLG MERSKGTMDF ILSLPYNRSQ IFQTKFWLGG FVIVLSQLIG
121: FLLAWLLILV YNPEHVYFFE HSSIGVIVIS FMAFSLVMAA GALTGNAFAQ LLTAFSAAIL
181: PYLIIALPVG NLEVVFGANI WEIFPSPESY FSLASNLSNL VPISYVVNEW LINSKYLLLI
241: PAVMSMLFYL IGFISFKKLP SERNGHFFLW NRLDRPVQIL VMAFGILGFG LFGYYTGHSI
301: IGYILGMIIG AVAGFFVSYF SIYKKTKV