3.A.1.122.19
ABC3-type efflux porter, YtrEF, encoded within an operon, ytrABCDEF, apparently encoding two ABC exporters, one, YtrBCD, with TC# 3.A.1.153.1, and the other, this one. The operon is induced in early stationary phase under the control of YtrA, a GntR-type HTH transcriptional regulator, probably a repressor (Yoshida et al. 2000). These authors suggest this operon may be involve in acetoin secretion and/or reutilization, but it has also been suggested that it also plays a role in peptidoglycan (cell wall) biogenesis (Rismondo and Schulz 2021).
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| Accession Number: | O35005 |
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| Protein Name: | ABC transporter permease YtrF |
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| Length: | 436 |
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| Molecular Weight: | 48421.00 |
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| Species: | Bacillus subtilis (strain 168) [224308] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Lipid-anchor2 |
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| Substrate |
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1: MRFKDQVHFI RRNMKKNRLR VFMTILATTM ACAFLVVLSS VGFGIQKTIT DMTMSQQIVT
61: KVSVMGKEGD KPIKKADLEK YDHVRSVVER TQVYEPNKAT LGNRTNESSN LIFTNMNDEL
121: KANMELEKGR VAKSENEIVV GYDFAKRLLT KKESEEYNKK IEEAKGNPED IKEPKGYTKD
181: ILNKTIELSV SKTDSKTGDV TKTKTYDFKI VGITKKPSQD WMEDSNIFIS DQFKKDFSEF
241: LDFKGGNVET NIGVFADKFE NVEQLTNDLT DDGYYVTSVT TELEGANTFF MVFKIGLIFV
301: GCIAVIISAI GIFNTMTMAV TERTQEIGIM KAIGASPSII RRMFLMESAY IGILGCVIGI
361: IISYGVSYLV NLAVPMILAA TSGGDAGDLN YTFSYIPASL VIIAVVICGG VAVISGMNPA
421: RKATKTNVLT ALRREL