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3.A.7.2.1 Trw conjugation system of E. coli plasmid IncP. The hexameric form of TrwK is a catalytically active ATPase, much like the structurally related protein TrwB, the conjugative coupling protein (Arechaga et al, 2008), which is a structure-specific DNA-binding protein (Matilla et al., 2010)
Accession Number:	O50331
Protein Name:	TrwJ
Length:	226
Molecular Weight:	24782.00
Species:	Escherichia coli [562]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Host membrane¹ / Multi-pass membrane protein²
Substrate	protein polypeptide chain

Pfam:	PF07996
References (9) [1] “Genetic organization of the region involved in conjugative pilus synthesis, export and assembly of the incW plasmid R388.” Bolland S.et.al. 9325277 [2] “Functional analysis of unique class II insertion sequence IS1071.” Sota M.et.al. 16391056 [3] “DNA sequence of a plasmid-encoded dihydrofolate reductase.” Swift G.et.al. 7022127 [4] “Site-specific recombination promotes linkage between trimethoprim-and sulfonamide resistance genes. Sequence characterization of dhfrV and sulI and a recombination active locus of Tn21.” Sundstroem L.et.al. 3054482 [5] “Structural and functional analysis of the origin of conjugal transfer of the broad-host-range IncW plasmid R388 and comparison with the related IncN plasmid R46.” Llosa M.et.al. 2038309 [6] “Genetic organization of the conjugal DNA processing region of the IncW plasmid R388.” Llosa M.et.al. 8289274 [7] “Integrons found in different locations have identical 5' ends but variable 3' ends.” Hall R.M.et.al. 7929000 [8] “Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.” Partridge S.R.et.al. 11959558 [9] “The VirB4 family of proposed traffic nucleoside triphosphatases: common motifs in plasmid RP4 TrbE are essential for conjugation and phage adsorption.” Rabel C.et.al. 12533481

Pfam:

PF07996

References (9)

[1] “Genetic organization of the region involved in conjugative pilus synthesis, export and assembly of the incW plasmid R388.” Bolland S.et.al. 9325277

[2] “Functional analysis of unique class II insertion sequence IS1071.” Sota M.et.al. 16391056

[3] “DNA sequence of a plasmid-encoded dihydrofolate reductase.” Swift G.et.al. 7022127

[4] “Site-specific recombination promotes linkage between trimethoprim-and sulfonamide resistance genes. Sequence characterization of dhfrV and sulI and a recombination active locus of Tn21.” Sundstroem L.et.al. 3054482

[5] “Structural and functional analysis of the origin of conjugal transfer of the broad-host-range IncW plasmid R388 and comparison with the related IncN plasmid R46.” Llosa M.et.al. 2038309

[6] “Genetic organization of the conjugal DNA processing region of the IncW plasmid R388.” Llosa M.et.al. 8289274

[7] “Integrons found in different locations have identical 5' ends but variable 3' ends.” Hall R.M.et.al. 7929000

[8] “Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.” Partridge S.R.et.al. 11959558

[9] “The VirB4 family of proposed traffic nucleoside triphosphatases: common motifs in plasmid RP4 TrbE are essential for conjugation and phage adsorption.” Rabel C.et.al. 12533481

UniProt (Universal Protein Resource)
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FASTA formatted sequence

1:	MKKLVMTAAV AAILGAASPV MAQGIPVFDG TRALDFVQQF ARMKEQLDTA KDQLAEAQRM 
61:	YEAVTGGRGL GDLMRNAQLR EYLPDDLRTV YDSANGGGYS GISGSINDIL RDERLNGSVA 
121:	DMRRSIEERS RTARTTDKAV GCGPTKGHSN ASRRLKDEIS RTQDQKAIEE LQARIAGEQA 
181:	AIQNETTKLQ MIAQLRQAEQ ALISEQRRER NMPILSSGNQ GMPTIQ

3.A.7.2.1
Trw conjugation system of E. coli plasmid IncP. The hexameric form of TrwK is a catalytically active ATPase, much like the structurally related protein TrwB, the conjugative coupling protein (Arechaga et al, 2008), which is a structure-specific DNA-binding protein (Matilla et al., 2010)

Cross database links:

References (9)

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3.A.7.2.1Trw conjugation system of E. coli plasmid IncP. The hexameric form of TrwK is a catalytically active ATPase, much like the structurally related protein TrwB, the conjugative coupling protein (Arechaga et al, 2008), which is a structure-specific DNA-binding protein (Matilla et al., 2010)

Cross database links:

References (9)

External Searches:

Analyze:

3.A.7.2.1
Trw conjugation system of E. coli plasmid IncP. The hexameric form of TrwK is a catalytically active ATPase, much like the structurally related protein TrwB, the conjugative coupling protein (Arechaga et al, 2008), which is a structure-specific DNA-binding protein (Matilla et al., 2010)