3.A.1.27.5
The Mce/Yrb/Mlk (Mammalian cell entry) ABC-type putative steroid uptake transporter (involved in several aspects of mycobacterial pathogenesis) (Mohn et al., 2008; Joshi et al., 2006).
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| Accession Number: | O53545 |
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| Protein Name: | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4B |
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| Length: | 280 |
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| Molecular Weight: | 29563.00 |
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| Species: | mycobacterium tuberculosis [1773] |
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| Number of TMSs: | 5 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
steroid |
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| RefSeq: |
NP_218017.1
NP_338149.1
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| Entrez Gene ID: |
888336
922892
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| Pfam: |
PF02405
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| KEGG: |
mtc:MT3604
mtu:Rv3500c
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[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T. et.al. 9634230
[2] “Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv.” Camus J.-C. et.al. 12368430
[3] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.” Fleischmann R.D. et.al. 12218036
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1: MSYDVTIRFR RFFSRLQRPV DNFGEQALFY GETMRYVPNA ITRYRKETVR LVAEMTLGAG
61: ALVMIGGTVG VAAFLTLASG GVIAVQGYSS LGDIGIEALT GFLSAFLNVR VVAPVIAGIA
121: LAATIGAGAT AQLGAMRVSE EIDAVECMAV HSVSYLVSTR LIAGLVAIIP LYSLSVLAAF
181: FAARFTTVFV NGQSAGLYDH YFNTFLIPSD LLWSFMQAIA MSIAVMLVHT YYGYNASGGS
241: VGVGVAVGQA VRTSLIVVVV ITLFISLAVY GASGNFNLSG