3.A.1.27.5 The Mce/Yrb/Mlk (Mammalian cell entry) ABC-type putative steroid uptake transporter (involved in several aspects of mycobacterial pathogenesis) (Mohn et al., 2008; Joshi et al., 2006).
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Accession Number: | O53546 |
Protein Name: | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A |
Length: | 254 |
Molecular Weight: | 26640.00 |
Species: | mycobacterium tuberculosis [1773] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate |
steroid |
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RefSeq: |
NP_218018.1
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Entrez Gene ID: |
888320
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Pfam: |
PF02405
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KEGG: |
mtu:Rv3501c
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[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T. et.al. 9634230
[2] “Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv.” Camus J.-C. et.al. 12368430
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1: MIQQLAVPAR AVGGFFEMSM DTARAAFRRP FQFREFLDQT WMVARVSLVP TLLVSIPFTV
61: LVAFTLNILL REIGAADLSG AGTAFGTITQ LGPVVTVLVV AGAGATAICA DLGARTIREE
121: IDAMRVLGID PIQRLVVPRV LASTLVALLL NGLVCAIGLS GGYAFSVFLQ GVNPGAFING
181: LTVLTGLREL ILAEIKALLF GVMAGLVGCY RGLTVKGGPK GVGNAVNETV VYAFICLFVI
241: NVVMTAIGVR ISAQ