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8.A.21.2.1
Stomatin homologue. Cleavage of this protein by a protease encoded within the same operon as the stomatin has been reported to open an ion channel (Yokoyama and Matsui, 2005).

Accession Number:O59179
Protein Name:Protease; aka NfeD
Length:441
Molecular Weight:48281.00
Species:Pyrococcus horikoshii [53953]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass membrane protein2
Substrate

Cross database links:

RefSeq: NP_143370.1   
Entrez Gene ID: 1443826   
Pfam: PF00574    PF01957   
BioCyc: PHOR70601:PH1510-MONOMER   
KEGG: pho:PH1510   

Gene Ontology

GO:0004252 F:serine-type endopeptidase activity
GO:0006508 P:proteolysis

References (1)

[1] “Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.”  Kawarabayasi Y.et.al.   9679194
Structure:
2DEO   3BPP   3VIV   3WG5   3WWV   6M4B     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MRRILLSMIV LIFLASPILA KNIVYVAQIK GQITSYTYDQ FDRYITIAEQ DNAEAIIIEL 
61:	DTPGGRADAM MNIVQRIQQS KIPVIIYVYP PGASAASAGT YIALGSHLIA MAPGTSIGAC 
121:	RPILGYSQNG SIIEAPPKIT NYFIAYIKSL AQESGRNATI AEEFITKDLS LTPEEALKYG 
181:	VIEVVARDIN ELLKKSNGMK TKIPVNGRYV TLNFTNVEVR YLAPSFKDKL ISYITDPNVA 
241:	YLLLTLGIWA LIIGFLTPGW HVPETVGAIM IILAIIGFGY FGYNSAGILL IIVAMLFFIA 
301:	EALTPTFGLF TVAGLITFII GGILLFGGGE EYLVRKEVFS QLRILIITVG AILAAFFAFG 
361:	MAAVIRAHKK KARTGKEEMI GLIGTVVEEL NPEGMIKVRG ELWKARSKFN GKIEKGEKVR 
421:	VVDMDGLTLI VVRERKEGGE K