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1.C.36.5.1
IIICP protein complex SseB/SseC/SseD; SseB: translocon sheath protein; SseC and SseD: translocon pore subunits of the Salmonella pathogenicity island 2 (SPI2)

Accession Number:O84947
Protein Name:Secreted effector protein sseC
Length:484
Molecular Weight:52777.00
Species: [90371]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Secreted1
Substrate protein polypeptide chain

Cross database links:

RefSeq: NP_460365.1   
Entrez Gene ID: 1252918   
BioCyc: STYP99287:STM1400-MON   
KEGG: stm:STM1400   

Gene Ontology

GO:0009986 C:cell surface
GO:0005576 C:extracellular region
GO:0009405 P:pathogenesis
GO:0030254 P:protein secretion by the type III secretion...

References (6)

[1] “Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages.”  Hensel M.et.al.   9786193
[2] “Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival.”  Cirillo D.M.et.al.   9786194
[3] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609
[4] “Genetic determinants and polymorphisms specific for human-adapted serovars of Salmonella enterica that cause enteric fever.”  Tracz D.M.et.al.   16757591
[5] “Salmonella pathogenicity island 2-encoded proteins SseC and SseD are essential for virulence and are substrates of the type III secretion system.”  Klein J.R.et.al.   11159962
[6] “SseBCD proteins are secreted by the type III secretion system of Salmonella pathogenicity island 2 and function as a translocon.”  Nikolaus T.et.al.   11567004

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNRIHSNSDS AAGVTALTHH HLSNVSCVSS GSLGKRQHRV NSTFGDGNAA CLLSGKISLQ 
61:	EASNALKQLL DAVPGNHKRP SLPDFLQTNP AVLSMMMTSL ILNVFGNNAQ SLCQQLERAT 
121:	EVQNALRNKQ VKEYQEQIQK AIEQEDKARK AGIFGAIFDW ITGIFETVIG ALKVVEGFLS 
181:	GNPAEMASGV AYMAAGCAGM VKAGAETAMM CGADHDTCQA IIDVTSKIQF GCEAVALALD 
241:	VFQIGRAFMA TRGLSGAAAK VLDSGFGEEV VERMVGAGEA EIEELAEKFG EEVSESFSKQ 
301:	FEPLEREMAM ANEMAEEAAE FSRNVENNMT RSAGKSFTKE GVKAMAKEAA KEALEKCVQE 
361:	GGKFLLKKFR NKVLFNMFKK ILYALLRDCS FKGLQAIRCA TEGASQMNTG MVNTEKAKIE 
421:	KKIEQLITQQ RFLDFIMQQT ENQKKIEQKR LEELYKGSGA ALRDVLDTID HYSSVQARIA 
481:	GYRA