1.C.21.2.4 Two component Lacticin 3147 (Ltnα of 59 aas and Ltnβ of 65 aas (Draper et al. 2015). Lacticin 3147 and other lantibiotics target Lipid II to
inhibit cell wall synthesis, and then form pores in the membrane (Biswas and Biswas 2014). They target a large number of bacteria, and several mechanisms of pore-formation have been proposed (Draper et al. 2015).
|
Accession Number: | O87236 |
Protein Name: | Lantibiotic lacticin 3147 A1 |
Length: | 59 |
Molecular Weight: | 6798.00 |
Species: | Lactococcus lactis subsp. lactis [1360] |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
molecule, water, polyelectrolyte macromolecule |
---|
1: MNKNEIETQP VTWLEEVSDQ NFDEDVFGAC STNTFSLSDY WGNNGAWCTL THECMAWCK