1.M.1.1.1 The Spanin1 (Rz; inner membrane, IM)/Spanin2 (Rz1; outer membrane, OM) complex. Spanin1, 153 aas; Spanin2, 60 aas. Together they span the periplasm and mediate fusion of the IM and OM. By doing so, they disrupt the double membrane barrier (Berry et al. 2008; Rajaure et al. 2015; Kongari et al. 2018).
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Accession Number: | P00726 |
Protein Name: | Spanin, inner membrane subunit |
Length: | 153 |
Molecular Weight: | 17230.00 |
Species: | Enterobacteria phage lambda [10710] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Host cell inner membrane1 / Single-pass type II membrane protein2 |
Substrate |
molecule |
---|
1: MSRVTAIISA LVICIIVCLS WAVNHYRDNA ITYKAQRDKN ARELKLANAA ITDMQMRQRD
61: VAALDAKYTK ELADAKAEND ALRDDVAAGR RRLHIKAVCQ SVREATTASG VDNAASPRLA
121: DTAERDYFTL RERLITMQKQ LEGTQKYINE QCR