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3.A.15.2.1
The pilin secretion/fimbrial assembly system. The PilB and PilT ATPases act antagonistically in Type IV pilus function in Myxococcus xanthus. ATP binding and hydrolysis by PilT are essential for T4P extension while ATP binding and hydrolysis by PilB are essential for T4P retraction. Thus, PilB and PilT act at distinct steps in the T4P extension/retraction cycle (Jakovljevic et al., 2008).

Accession Number:P04739
Protein Name:PilA aka FIMA aka PA4525
Length:149
Molecular Weight:15512.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Fimbrium1
Substrate

Cross database links:

RefSeq: NP_253215.1   
Entrez Gene ID: 878423   
Pfam: PF07963    PF00114   
BioCyc: PAER208964:PA4525-MONOMER   
KEGG: pae:PA4525   

Gene Ontology

GO:0009289 C:pilus
GO:0007155 P:cell adhesion

References (4)

[1] “Comparative studies of the amino acid and nucleotide sequences of pilin derived from Pseudomonas aeruginosa PAK and PAO.”  Sastry P.A.et.al.   2997119
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043
[3] “Mutations in the fifth-position glutamate in Pseudomonas aeruginosa pilin affect the transmethylation of the N-terminal phenylalanine.”  Macdonald D.L.et.al.   8330261
[4] “Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design.”  Campbell A.P.et.al.   8845350
Structure:
1PAN   1PAO     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKAQKGFTLI ELMIVVAIIG ILAAIAIPQY QNYVARSEGA SALATINPLK TTVEESLSRG 
61:	IAGSKIKIGT TASTATETYV GVEPDANKLG VIAVAIEDSG AGDITFTFQT GTSSPKNATK 
121:	VITLNRTADG VWACKSTQDP MFTPKGCDN