Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.72.1.1
Pertussis toxin

Accession Number:P04978
Protein Name:PTX S2
Length:226
Molecular Weight:24799.00
Species:Bordetella pertussis [520]
Location1 / Topology2 / Orientation3: Secreted1
Substrate toxin

Cross database links:

RefSeq: NP_882283.1   
Entrez Gene ID: 2665069   
Pfam: PF03440    PF02918   
BioCyc: BPER257313:BP3784-MONOMER   
KEGG: bpe:BP3784   

Gene Ontology

GO:0020002 C:host cell plasma membrane
GO:0016020 C:membrane
GO:0005488 F:binding
GO:0009405 P:pathogenesis

References (5)

[1] “Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.”  Nicosia A.et.al.   2873570
[2] “Pertussis toxin gene: nucleotide sequence and genetic organization.”  Locht C.et.al.   3704651
[3] “Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.”  Parkhill J.et.al.   12910271
[4] “The crystal structure of pertussis toxin.”  Stein P.E.et.al.   8075982
[5] “Crystal structure of the pertussis toxin-ATP complex: a molecular sensor.”  Hazes B.et.al.   8637000
Structure:
1BCP   1PRT   1PTO   6RO0     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MPIDRKTLCH LLSVLPLALL GSHVARASTP GIVIPPQEQI TQHGGPYGRC ANKTRALTVA 
61:	ELRGSGDLQE YLRHVTRGWS IFALYDGTYL GGEYGGVIKD GTPGGAFDLK TTFCIMTTRN 
121:	TGQPATDHYY SNVTATRLLS STNSRLCAVF VRSGQPVIGA CTSPYDGKYW SMYSRLRKML 
181:	YLIYVAGISV RVHVSKEEQY YDYEDATFET YALTGISICN PGSSLC