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3.D.3.3.1
Ubiquinol:cytochrome c oxidoreductase.  The cytochrome bc1 complex resides in the inner membrane of mitochondria and transfers electrons from ubiquinol to cytochrome c. This electron transfer is coupled to the translocation of protons across the membrane by the protonmotive Q cycle mechanism. This mechanism topographically separates reduction of quinone and reoxidation of quinol at sites on opposite sites of the membrane, referred to as the center N (Qn site) and the center P (Qp site), respectively. Both are located on cytochrome b, a transmembrane protein of the bc1 complex that is encoded on the mitochondrial genome (Ding et al. 2006).

Accession Number:P07143
Protein Name:CY1 aka CTC1 aka CYT1 aka YOR065W aka YOR29-16
Length:309
Molecular Weight:34055.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Single-pass membrane protein2 / Intermembrane side3
Substrate hydron

Cross database links:

DIP: DIP-4166N
RefSeq: NP_014708.1   
Entrez Gene ID: 854231   
Pfam: PF02167   
KEGG: sce:YOR065W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005750 C:mitochondrial respiratory chain complex III
GO:0045153 F:electron transporter, transferring electron...
GO:0020037 F:heme binding
GO:0005515 F:protein binding
GO:0006122 P:mitochondrial electron transport, ubiquinol...
GO:0006810 P:transport

References (6)

[1] “Sequencing of the nuclear gene for the yeast cytochrome c1 precursor reveals an unusually complex amino-terminal presequence.”  Sadler I.et.al.   6092058
[2] “The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the presence of two tRNAs and 24 new open reading frames.”  Valens M.et.al.   9133743
[3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[4] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[5] “Structure at 2.3 A resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.”  Hunte C.et.al.   10873857
[6] “Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c.”  Lange C.et.al.   11880631
Structure:
1EZV   1KB9   1KYO   1P84   2IBZ   3CX5   3CXH   4PD4   6GIQ   6HU9   [...more]

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFSNLSKRWA QRTLSKSFYS TATGAASKSG KLTQKLVTAG VAAAGITAST LLYADSLTAE 
61:	AMTAAEHGLH APAYAWSHNG PFETFDHASI RRGYQVYREV CAACHSLDRV AWRTLVGVSH 
121:	TNEEVRNMAE EFEYDDEPDE QGNPKKRPGK LSDYIPGPYP NEQAARAANQ GALPPDLSLI 
181:	VKARHGGCDY IFSLLTGYPD EPPAGVALPP GSNYNPYFPG GSIAMARVLF DDMVEYEDGT 
241:	PATTSQMAKD VTTFLNWCAE PEHDERKRLG LKTVIILSSL YLLSIWVKKF KWAGIKTRKF 
301:	VFNPPKPRK