TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.5.5
Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K+ homeostasis) [SapD can stimulate the K+ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)

Accession Number:P0A2J5
Protein Name:Peptide transport system permease protein SapC aka STM1694
Length:296
Molecular Weight:31548.00
Species:Salmonella typhimurium [90371]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Cationic peptides

Cross database links:

RefSeq: NP_460652.1   
Entrez Gene ID: 1253212   
Pfam: PF00528   
BioCyc: STYP99287:STM1694-MONOMER   
KEGG: stm:STM1694   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0015833 P:peptide transport
GO:0015031 P:protein transport

References (2)

[1] “Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium.”  Parra-Lopez C.et.al.   8223423
[2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MPYDSVYSEK RPPGTLRTAW RKFYSDAPAM VGLYGCAGLA LLCIFGGWIA PYGIDQQFLG 
61:	YQLLPPSWSR YGEVSFFLGT DDLGRDVLSR LLSGAAPTVG GAFIVTLAAT LCGLVLGVVA 
121:	GATHGLRSAV LNHILDTLLS IPSLLLAIIV VAFAGPHLSH AMFAVWLALL PRMVRSVYSM 
181:	VHDELEKEYV IAARLDGATT LNILWFAILP NITAGLVTEI TRALSMAILD IAALGFLDLG 
241:	AQLPSPEWGA MLGDALELIY VAPWTVMLPG AAITLSVLLV NLLGDGIRRA IIAGVE