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3.A.1.5.5 Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K⁺ homeostasis) [SapD can stimulate the K⁺ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)
Accession Number:	P0A2J5
Protein Name:	Peptide transport system permease protein SapC aka STM1694
Length:	296
Molecular Weight:	31548.00
Species:	Salmonella typhimurium [90371]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	cationic peptidyl group

RefSeq:	NP_460652.1
Entrez Gene ID:	1253212
Pfam:	PF00528
BioCyc:	STYP99287:STM1694-MONOMER
KEGG:	stm:STM1694
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0005215 F:transporter activity GO:0015833 P:peptide transport GO:0015031 P:protein transport
References (2) [1] “Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium.” Parra-Lopez C.et.al. 8223423 [2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.” McClelland M.et.al. 11677609

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	MPYDSVYSEK RPPGTLRTAW RKFYSDAPAM VGLYGCAGLA LLCIFGGWIA PYGIDQQFLG 
61:	YQLLPPSWSR YGEVSFFLGT DDLGRDVLSR LLSGAAPTVG GAFIVTLAAT LCGLVLGVVA 
121:	GATHGLRSAV LNHILDTLLS IPSLLLAIIV VAFAGPHLSH AMFAVWLALL PRMVRSVYSM 
181:	VHDELEKEYV IAARLDGATT LNILWFAILP NITAGLVTEI TRALSMAILD IAALGFLDLG 
241:	AQLPSPEWGA MLGDALELIY VAPWTVMLPG AAITLSVLLV NLLGDGIRRA IIAGVE

3.A.1.5.5
Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K⁺ homeostasis) [SapD can stimulate the K⁺ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)

Cross database links:

Gene Ontology

References (2)

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3.A.1.5.5Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K+ homeostasis) [SapD can stimulate the K+ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

3.A.1.5.5
Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K⁺ homeostasis) [SapD can stimulate the K⁺ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)